Selective inhibitors of the urokinase plasminogen activator

Details Selective inhibitors of the urokinase plasminogen activator Selective inhibitors of the urokinase plasminogen activator

2007-04-24

2007-04-24

Kumar, Shailendra (Department: 1621)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

C514S595000, C514S634000, C206S569000, C206S568000

Reexamination Certificate

active

11058699

ABSTRACT:
The present invention relates to novel selective inhibitors of the urokinase plasminogene activator (uPA, EC3,4.21.31) of the aryl guanidine type.

REFERENCES:
patent: 3257411 (1966-06-01), Patchett et al.
patent: 5914319 (1999-06-01), Schacht et al.
patent: 441366 (1968-01-01), None
patent: 947552 (1956-09-01), None
patent: WO 9920608 (1999-04-01), None
Carter et al., Chemotherapy of Cancer, second edition, John Wiley & Sons, N.Y., N.Y., 1981, pp. 362-365.
Y. Heechung et al., “Selective Inhibition of Urokinase by Substituted Phenylguanidines: Quantitative Structure-Activity Relationship Analyses,” Journal of Medicinal Chemistry, American Chemical Society, vol. 33, No. 11, 1990, p. 2956-2961.
R. Rai et al., “Guanidinophenyl-substituted enol lactones as selective, mechanism-based inhibitors of trypsin-like serine proteases,” Journal of Medicinal Chemistry, vol. 35, No. 22, 1992, p. 4150-9.
W. Bollag et al. “Substituted Benzylhydrazines”, Chemical Abstracts, vol. 69, No. 9, Aug. 26, 1968, abstract No. 35691c, p. 3321.

Affiliated with

Also associated with

Rating

Selective inhibitors of the urokinase plasminogen activator does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Selective inhibitors of the urokinase plasminogen activator, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Selective inhibitors of the urokinase plasminogen activator will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3798509