Carbapenem compounds

Details Carbapenem compounds Carbapenem compounds

2007-04-17

2007-04-17

Wilson, James O. (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C540S302000

Reexamination Certificate

active

10494603

ABSTRACT:
A compound or its pharmaceutically acceptable salt represented by the following formula:The invention is a carbapenem compound which has a potent antibacterial activity over a broad range of Gram negative and Gram positive bacteria, especially penicillin-resistantStreptococcus pneumoniae(PRSP) which has been isolated at an elevated frequency in recent years and thus causes a serious clinical problem, andHaemophilus influenzaewhich has acquired resistance against the existing β-lactam antibiotics over a wide scope due to penicillin-binding protein (PBP) mutations such as β-lactamase non-producing ampicillin-resistant (BLNAR)Haemophilus influenzae, and has excellent oral absorbability.

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