Purified polypeptides from Streptococcus pneumoniae

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C536S023200, C435S320100, C530S350000

Reexamination Certificate

active

11403784

ABSTRACT:
The invention provides novel polypeptides and polynucleotides encoding such polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing such polypeptides to screen for antibacterial compounds.

REFERENCES:
patent: 5302527 (1994-04-01), Birkett et al.
patent: 5539132 (1996-07-01), Royer et al.
patent: 5614551 (1997-03-01), Dick et al.
patent: 5759837 (1998-06-01), Kuhajda et al.
patent: 5965402 (1999-10-01), Black et al.
patent: 6228619 (2001-05-01), Foster et al.
patent: 6274376 (2001-08-01), Black et al.
patent: 6380370 (2002-04-01), Doucette-Stamm et al.
patent: 6403337 (2002-06-01), Bailey et al.
patent: 6432670 (2002-08-01), Payne et al.
patent: 6593114 (2003-07-01), Kunsch et al.
patent: 6753172 (2004-06-01), Payne et al.
patent: 6821746 (2004-11-01), DeWolf, Jr. et al.
patent: 6951729 (2005-10-01), Dewolf et al.
patent: 6995254 (2006-02-01), Payne et al.
patent: 7033795 (2006-04-01), DeWolf, Jr. et al.
patent: 7048926 (2006-05-01), Brandt et al.
patent: 2002/0076766 (2002-06-01), Black et al.
patent: 2004/0053814 (2004-03-01), Brandt et al.
patent: 2005/0112713 (2005-05-01), DeWolf et al.
patent: 2006/0083755 (2006-04-01), Black et al.
patent: 26 20 777 (1977-01-01), None
patent: 0 78 6519 (1997-07-01), None
patent: 0 826 774 (1998-03-01), None
patent: 10-174590 (1998-06-01), None
patent: WO 97/30070 (1997-08-01), None
patent: WO 97/30149 (1997-08-01), None
patent: WO 00/70017 (2000-11-01), None
patent: WO 01/30988 (2001-05-01), None
patent: WO 01/48248 (2001-07-01), None
patent: WO 02/31128 (2002-04-01), None
Sequence search alignments between Accession No. AAZ96201 and Applicants' SEQ ID No. 1.
Sequence search alignment between Accession No. AAY85822 and Applicants' SEQ ID No. 2.
Bergler et al., “Protein EnvM is the NADH-dependent Enoyl-ACP Reductase (Fabl) ofEschericia coli*” The Journal of Biological Chemistry, vol. 269, No. 8, pp. 5493-5496 (1994).
Bergler et al., “Sequences of theenvMgene and of two mutated alleles inEscherichia coli”, Journal of General Microbiology (1992), 138; pp. 2093-2100.
Broadwater et al., “Spinach Holo-Acyl Carrier Protein: Overproduction and Phosphopantetheinylation inEscherichia coliBL21(DE3), in Vitro Acylation, and Enzymatic Desaturation of Histidine-Tagged Isoform 11”, Protein Expression and Purification 15, 314-326 (1999).
Edwards, et al., “Cloning of the fabF gene in an expression vector and in vitro characterization of recombinantfabFandfabBencoded enzymes fromEscherichia coli”, FEBS Letters, 402:62-66 (1997).
Grassberger et al., “Preparation and Antibacterial Activates of New 1,2,3-Diazaborine Derivatives and Analogues”, Journal of Medicinal Chemistry, 1984. vol. 24, No. 8, pp. 947-953.
Gronowitz et al., “Antibacterial borazaro derivatives”, Acta Pharm. Succica 8, pp. 377-390 (1971).
Heath et al., “Enoyl-Acyl Carrier Protein Reductase (fabI) Plays a Determinant Role in Completing Cycles of Fatty Acid Elongation inEscherichia coli*”, The Journal of Biological Chemistry, vol. 270, No. 44, pp. 26538-26542 (1995).
Heath et al., “Regulation of Fatty Acid Elongation and Initiation by Acyl-Acyl Carrier Protein inEscherichia coli*”, The Journal of Biological Chemistry, vol. 271, No. 4, pp. 1833-1836 (1996).
Lam et al., “Effect of diazaborine derivatives (Sa 84.474) on the virulence ofEscherichia coli”, Journal of Antimicrobial Chemotherapy (1987) 20, pp. 37-45.
Lambalot, et al., “Cloning, Over production, and Characterization of theEscherichia coliHolo-acyl Carrier Protein Synthase*”, The Journal of Biological Chemistry, vol. 270, No. 42, pp. 24658-24661 (1995).
Ngo et al., “Computational complexity, protein structure prediction, and the Levinthal paradox”, Chapter 14 in ‘The Protein Folding Problem and Tertiary Structure Prediction’, Merz et al. (eds.), Birkhauser: Boston, MA, pp. 433 & 492-495.
Rock et al., “Preparative Enzymatic Synthesis and Hydrophobic Chromatography of Acyl-Acyl Carrier Protein”,The Journal of Biological Chemistry, 254(15): 7123-7128 (1979).
Rock et al., “Acyl Carrier Protein fromEscherichia coli”, Methods in Enzymology, 71:341-351 (1981).
Roujeinkova et al., “Inhibitor Binding Studies on Enoyl Reductase Reveal Conformational Changes Related to Substrate Recognition”,The Journal of Biological Chemsitry, 274(43): 30811-30817 (1999).
Turnowsky et al., “envM genes ofSalmonella typhimuriumandEscherichia coli”, Journal of Bacteriology, Dec. 1989 pp. 6555-6565.
Ward et al, “Kinetic and Structural Characteristics of the Inhibition of Enoyl (Acyl Carrier Protein) Reductase by Triclosan”, Biochemistry, 38: 12514-12525 (1999).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Purified polypeptides from Streptococcus pneumoniae does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Purified polypeptides from Streptococcus pneumoniae, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Purified polypeptides from Streptococcus pneumoniae will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3784642

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.