Promoter for smooth muscle cell expression

Details Promoter for smooth muscle cell expression Promoter for smooth muscle cell expression

2007-01-30

2007-01-30

Ketter, James (Department: 1636)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C435S455000, C435S377000, C623S001130, C623S001410

Reexamination Certificate

active

09381750

ABSTRACT:
Disclosed is a smooth muscle cell specific promoter, the SM22α gene promoter as well as the murine cDNA and genomic SM22α nucleic acid sequences. Also disclosed are methods of preventing restenosis following balloon angioplasty and methods of treating asthma based on inhibition of smooth muscle cell proliferation by expressing cell cycle control genes, or contraction inhibiting peptides in smooth muscle cells, under the control of the SM22α promoter.

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