DNA molecules encoding ligand gated ion channels from...

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

Reexamination Certificate

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C435S325000, C435S348000, C536S023100, C536S023500, C530S350000

Reexamination Certificate

active

10239420

ABSTRACT:
The present invention relates in part to isolated nucleic acid molecules (polynucleotides) which encodeDermacentor variabilisligand gated ion channel proteins. The present invention also relates to recombinant vectors and recombinant hosts which contain a DNA fragment encodingD. variabilisLGIC/GluCl channels, substantially purified forms of associatedD. variabilischannel proteins and recombinant membrane fractions comprising these proteins, associated mutant proteins, and methods associated with identifying compounds which modulate associatedDermacentor variabilisLGIC/GluCl, which will be useful as insecticides and acaracides.

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