Phantom for production of controllable fMRI signal

Electricity: measuring and testing – Particle precession resonance – Spectrometer components

Reexamination Certificate

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C324S311000

Reexamination Certificate

active

10957822

ABSTRACT:
The subject invention relates to a method and apparatus for producing stimulated MRI data. In an embodiment, a remote-controlled “smart phantom” can produce simulated data. The simulated data can be acquired from a MRI system. The subject device can generate control signals and send the generated control signals to secondary coils/probes placed in the subject smart phantom. The control signals determine the current flow in the secondary coils/probes, which act as local spin magnetization amplifiers and thus produce regions of variable contrast to noise ratio. The control signals can be generated with various parameters, such as BOLD models, different levels of contrast-to-noise ratio (CNR), signal intensities, and physiological signals. Comparisons can be made with the widely-used simulated data by computers. Validation of the subject smart phantom can be performed with both theoretical analysis and data of human subjects.

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