Compounds, compositions, and methods

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C544S182000

Reexamination Certificate

active

10529630

ABSTRACT:
1,2,4-Triazin-5-ones useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed.

REFERENCES:
patent: 6303603 (2001-10-01), Patoiseau et al.
West, Anthony R., Solid State Chemistry and its Applications, Wiley, New York, 1988, pp. 358 & 365.
Vippagunta et al., Advanced Drug Delivery Reviews 48: 3-26, 2001.
Cecil Textbook of Medicine, edited by Bennet, J.C., and Plum F., 20th edition,vol. 1, 1004-1010, 1996.
Haque et al. Cell Motility and Cytoskeleton, 58: 10-16, 2004.
Yildiz et al., Trends in Cell Biology, 15(7):112-120, 2005.
Maliga et al., Chem. Biol. 9(9): 989-996,2002.
International Search Report mailed Jun. 10, 2004, for Application No. PCT/US03/32318, filed Oct. 9, 2003.
International Preliminary Examination Report mailed Jul. 16, 2004, for Application No. PCT/US03/32318, filed Oct. 9, 2003.

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