Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2007-04-10
2007-04-10
Saoud, Christine J. (Department: 1647)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
C530S300000, C530S402000, C435S069700, C435S069800
Reexamination Certificate
active
10063532
ABSTRACT:
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
REFERENCES:
patent: 5536637 (1996-07-01), Jacobs
patent: 6001963 (1999-12-01), Bergsma et al.
patent: 6025156 (2000-02-01), Gwynn et al.
patent: 6124433 (2000-09-01), Falb et al.
patent: 6156500 (2000-12-01), Falb
patent: 6162604 (2000-12-01), Jacob
patent: 6228582 (2001-05-01), Rodier et al.
patent: 6395306 (2002-05-01), Cui et al.
patent: 6399349 (2002-06-01), Ryan et al.
patent: 6414117 (2002-07-01), Levinson
patent: 6465185 (2002-10-01), Goldfine et al.
patent: 6498235 (2002-12-01), Sheppard et al.
patent: 6562343 (2003-05-01), Levinson
patent: 6645499 (2003-11-01), Lal et al.
patent: 6730502 (2004-05-01), Van Hijum et al.
patent: 6737522 (2004-05-01), Sundick et al.
patent: WO 97/38085 (1997-10-01), None
Sen et al. Aneuploidy and cancer (2000), Curr. Opinion in Oncology, vol. 12, pp. 82-88.
Pennica et al. WISP genes are members of the connective tissue growth factor family that are up-regulated in Wnt-1-transformed cells and aberrantly expressed in human colon tumors (1998), PNAS, vol. 95, pp. 14717-14722.
Haynes et al., Proteome analysis: Biological Assay or data archive? (1998), Electophoresis, vol. 19, pp. 1862-1871.
Hu et al., Analysis of genomic and Proteomic Data using Advanced literature mining (2003), J. of Proteome Research, vol. 2, pp. 405-412.
Chen et al. Discordant Protein and mRNA Expression in Lung Adenocarcinomas (2002), Molecular and Cellular Proteomics, vol. 1, pp. 304-313.
Heddwen et al. cDNA array identification of genes regulated in rat renal medulla in response to vasopressin infusion (2003), Am. J. Physiol. Reanl Physiol., vol. 284: F218-F228.
Berner et al. Clinicopathological associations of CD44 mRNA and protein expression in primary breast carcinomas (2003), Histopathology, vol. 42, pp. 546-554.
Toler et al. Loss of communication in ovarian cancer (2006), Am. J. of Obs. Gyn., vol. 194, e27-e31.
Sugg et al. Cytoplasmic staining of erbB-2 but not mRNA levels correlates with differentiation in human thyroid neoplasia (1998), Clinical Endocrinology, vol. 49, pp. 629-637.
Oda et al. Expression of MDR1/p-glycoprotein and multidrug resistance-associated protein in childhood solid tumours (1997), Virchows Arch., vol. 430, pp. 99-105.
Klein et al Selection for Genes Encoding Secreted Proteins and ReceptorsProc Natl Acad Sci.93 7108-7113 (1996).
Database Search. DNA Sequence Alignments [BLASTN 2 2 1[Jul. 12, 2001]. NCBI].
Database Search Protein Sequence Alignments [BLASTN 2 2 1 [Jul. 12, 2001]. NCBI].
Alberts, et al. 1994.Molecular Biology of the Cell, 3rd Edition, pp. 403-404, 453. New York: Garland Publishing.
Alberts, et al. 2002.Molecular Biology of the Cell 4th Edition, pp. 302, 363-364, 379, 435. New York: Garland Publishing.
Grimaldi, et al. 1989. The t(5;14) chromosomal translocation in a case of acute lymphocytic leukemia joins the interleukin-3 to the immunoglobulin heavy chain gene.Blood,73(8):2081-2085.
Gygi, et al. Mar. 1999. Correlation between Protein and mRNA Abundance in Yeast.Molecular and Cellular Biology,1720-1730.
Hanna, et al. Aug. 1999. HER-2
eu breast cancer predictive testing.Pathology Associates Medical Laboratories.
Hyman et al. Nov. 2002. Impact of DNA Amplification of Gene Expression Patterns.Cancer Research, 62:6240-6245.
Lewin, B. 1994. Oncogenes: Gene Expression and Cancer, Chap. 39, pp. 1196-1201.Genes V.New York: Oxford University Press.
Lewin, B. 1997. Regulation of Transcription, Chap. 29, pp. 847-848.Genes VI.New York: Oxford University Press.
Meeker, et al. 1990. Activation of the interleukin-3 gene by chromosome translocation in acute lymphocytic leukemia with eosinophilia.Blood, 76(2):285-289.
Meric, et al. 2002. Translation initiation in cancer: A novel target for therapy.Molecular Cancer Therapeutics, 1:971-979.
Ørntoft, et al. 2002. Genome-wide study of gene copy numbers; transcripts, and protein levels in pairs of non-invasive and invasive human transitional cell carcinomas.Molecular&Cellular Proteomics,1:37-45.
Pollack, et al. 2002. Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors.PNAS, 99(20):12963-12968.
Singleton, et al. 1992. Clinical and pathologic significance of the c-erbB-2 (HER-2
eu) oncogene.Pathol. Annu,1(27):165-190.
Zhigang, et al. 2004. Prostate stem cell antigen (PSCA) expression in human prostate cancer tissues and its potential role in prostate carcinogenesis and progression of prostate cancer.World Journal of Surgical Oncology, 2:13.
2002-2003 Catalog & Technical Reference, New England BioLabs, Inc., p. 122.
Alberts, et al. 1994.Molecular Biology of the Cell, 3rd Edition,pp. 1216-1217. New York: Garland Publishing.
Allman, et al. 1996. BCL-6 expression during B-cell activation.Blood,87(12):5257-5268.
Anderson, et al. 1997. A comparison of selected mRNA and protein abundances in human liver.Electrophoresis,18:533-537.
Chen, et al. 2002. Discordant protein and mRNA expression in lung adenocarcinomas.Molecular&Cellular Proteomics 1.4, pp. 304-313.
Fessler, et al. 2002. A genomic and proteomic analysis of activation of the human neutrophil by lipopolysaccharide and its mediation by p38 mitogen-activated protein kinase.The Journal of Biological Chemistry,277(35):31291-31302.
Fu, et al. 1996. Translational regulation of human p53 gene expression.The EMBO Journal,15(16):4392-4401.
Gökmen-Polar, et al. 2001. Elevated protein kinase C βII is an early promotive event in colon carcinogenesis.Cancer Research,61:1375-1381.
Hanash, S. 2003. Making sense of microarray data to classify cancer.The Pharmacogenomics Journal,3:308-311.
Hanash, S. Mar. 2005. Integrated global profiling of cancer.Nature Reviews, Applied Proteomics Collection,pp. 9-14.
Hancock, W. S. 2004. Do we have enough biomarkers?Journal of Proteome Research,3(4):685.
Haynes, et al. 1998. Proteome analysis: Biological assay or data archive?Electrophoresis,19:1862-1871.
Hillier, et al. 1996. Generation and analysis of 280,000 human expressed sequence tags.Genome Res.6 (9), 807-828, Publication AA099445 (May 11, 1997).
Hu, et al. 2003. Analysis of genomic and proteomic data using advanced literature mining.Journal of Proteome Research,2:405-412.
Jang, et al. 1997. An examination of the effects of hypoxia, acidosis, and glucose starvation on the expression of metastatis-associated genes in murine tumor cells.Clin. Exp. Metastasis,15(5):469-483. (Abstract).
Konopka, et al. 1986. Variable expression of the translocatedc-abloncogene in Philadelphia-chromosome-positive B-lymphoid cell lines from chronic myelogenous leukemia patients.Proc. Natl. Acad. Sci. USA,83:4049-4052.
OHara, et al. 2001. Directional cDNA library construction assisted by thein vitrorecombination reaction.Nucleic Acids Research,29(4):e22 p. 1-8.
Powell, et al. 1998. Expression of cytochrome P4502E1 in human liver: Assessment by mRNA, genotype and phenotype.Pharmacogenetics,8:411-421. (Abstract).
Tokunaga, et al. 2000. Application of quantitative RT-PCR using “TaqMan” technology to evaluate the expression of CK 18 mRNA in various cell lines.J. Exp. Clin. Cancer Res.,19(3):375-381.
Vallejo, et al. 2000. Evidence of tissue-specific, post-transcriptional regulation of NRF-2 expression.Biochimie,82(12):1129-1133. (Abstract).
Wang, et al. 1996. mRNA Differential display: Application in the discovery of novel pharmacological targets.Trends Pharmacol. Sci.,17(8):276-279.
Abe, et al. “An increased high-mobility group A2 expression level is associated with malignant phenotype in pancreatic exocrine tissue.”Br J Cancer.Dec. 1, 2003;89(11):2104-9.
Ando, et al. “Selective apoptosis o
Goddard Audrey
Godowski Paul J.
Grimaldi J. Christopher
Gurney Austin L.
Wood William I.
Barnes Elizabeth M.
Genentech Inc.
Knobbe Martens Olsen & Bear LLP
Kresnak Mark T.
Saoud Christine J.
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