N-[4-(heteroarylmethyl)phenyl]-heteroarylamines

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

Other Related Categories

C514S248000, C514S243000, C514S280000, C546S112000, C546S114000, C546S139000, C546S268400, C546S272400, C544S133000, C544S135000, C544S139000, C544S141000, C548S254000, C548S262200, C548S266200, C548S300100

Type

Reexamination Certificate

Status

active

Patent number

10979362

Description

ABSTRACT:
The present invention is concerned with compounds of formulathe N-oxides, the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein R1is hydrogen, hydroxy, C1-6alkyl or aryl; R2is hydrogen; optionally substituted C1-12alkyl; C3-7cycloalkyl; C2-8alkenyl, optionally substituted pyrrolidinyl or aryl; R3is hydrogen, optionally substituted C1-6alkyl or aryl; Het is an optionally substituted unsaturated heterocycle selected from imidazolyl, triazolyl, tetrazolyl and pyridinyl;is an optionally substituted unsaturated mono- or bicyclic heterocycle; and aryl is optionally substituted phenyl. The present invention also relates to processes for their preparation and compositions comprising said new compounds, as well as their use as a medicine.

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patent: 6833375 (2004-12-01), Venet et al.
patent: 0 260 744 (1988-03-01), None
patent: 0 260 744 (1988-03-01), None
patent: 0 371 559 (1990-06-01), None
patent: WO 91/16314 (1991-10-01), None
patent: WO 96/15118 (1996-05-01), None
patent: WO 97/22596 (1997-06-01), None
patent: WO 97/30035 (1997-08-01), None

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