Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2007-05-01
2007-05-01
Stockton, Laura L. (Department: 1626)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C548S316400, C548S325100
Reexamination Certificate
active
10946418
ABSTRACT:
The present invention describes novel 1,3-dihydro-imidazol-2-one or 1,3-dihydro-imidazol-2-thione compounds of formula (I):or a stereoisomer or pharmaceutically acceptable salt or solvate thereof, wherein A, L R1, R2, R3and R4are defined in the present specification, which are useful as selective inhibitors of MMP, TACE, aggrecanase or a combination thereof. This invention also relates to pharmaceutical compositions comprising these compounds and methods of using the same.
REFERENCES:
patent: 2003/0130273 (2003-07-01), Sheppeck et al.
Glaβ et al., Archiv der Pharmazie (Weinheim, Germany) (1995), 328(10), pp. 709-719.
Chen Xiao-Tao
Gilmore John L.
He Xiaohua
Sheppeck James
Bristol Myers Squibb Company
Stockton Laura L.
Sun Jing G.
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