Prostamides for the treatment of glaucoma and related diseases

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C548S504000, C548S507000

Reexamination Certificate

active

10713500

ABSTRACT:
Disclosed herein are compositions comprising an amide related to a prostaglandin and an amine wherein the amine is selected from the group consisting of epinephrine, dopamine, serotonin, and analogs or prodrugs thereof. Also disclosed are certain chemical compounds, pharmaceutical compositions, and methods of treating glaucoma.

REFERENCES:
patent: 5688819 (1997-11-01), Woodward et al.
patent: 6376533 (2002-04-01), Burk et al.
patent: 6410591 (2002-06-01), Burk et al.
patent: 6531504 (2003-03-01), Burk et al.
patent: 6538018 (2003-03-01), Burk et al.
patent: 6586462 (2003-07-01), Burk et al.
patent: 0 458 587 (1991-11-01), None
patent: 50013363 (1975-02-01), None
patent: WO 03/047417 (2003-06-01), None
Dragoli, D.R., et al.,Parallel Synthesis of Prostaglandin E1 Analogues, J. Comb. Chem 1999, 1. p. 534-539.
Bezuglov, et al., Synthesis and Biological Evaluation of Novel Amides of Polyunsaturated Fatty Acids with Dopamine,Bioorganic&Medicinal Chemistry Letters11 (2001), 447-449).
Bezuglov, V.V., et al. Bioactive Amides of Fatty Acids,Biochemistry(Moscow), vol. 63, No. 1 1998, pp. 22-30.
Bezuglov, V.V., et al., Arachidonoylcholine and N,N-dimethylaminoethyl arachidonate, new cholinergic compounds,Russian Journal of Bioorganic Chemistry, vol. 27, No. 3, 2001, pp. 200-203.
Bezuglov, V.V., et al., Stereochemistry of substitution of allylic hydroxyl with fluorine in prostaglandins.Russian Journal of bioorganic Chemistry, vol. 22, No. 10, 1996, pp. 688-695.
Bezuglov, V.V., et al., Synthesis of novel coumarin-3-carboxylic acid derivatives as chemical detectors of hydroxyl radicals in biological systems,Russian Journal of Bioorganic Chemistry, vol. 23, No. 4, 1997, pp. 288-291.
Bisogno, T., et al., N-acyl-dopamines: novel synthetic CB1 cannabinoid-receptor ligands and inhibitors of anandamide inactivation with cannabimimetic activity in broto and in vivo,Biochem J., 2000, 351, pp. 817-824.
Bito, L.Z., Prostaglandins, other eicosanoids, and their derivatives as potential antiglaucoma agents, Chpt. 20,Applied Pharmacology in the medical treatment of glaucoma, Drance, S.M. et al., NY, Grune & Stratton, 1984, pp. 477-505.
Bito, L.Z., Prostaglandins Old concepts and new perspectives,Arch Ophthalmol, vol. 105, pp. 1036-1039 (1987).
English, D., et al., Messenger functions of phosphatidic acid,Chemistry of physics of lipids, 80, 1996, 117-132.
Janusz, J. M. et al., Vanilloids. 1. analogs of capsaicin with antinociceptive and anti-inflammatory activity,J. Med Chem. 1993, 2595-2604.
Kulikov, V.I., et al., Bioactive amide of prostaglandin E1 and ethanolamine plasmalogen analog of platelet-activating factor inhibits several pathways of human platelet aggregation,Biochemistry(Moscow), vol. 65, No. 4, 2000 pp. 427-430.
Nilsson, S., et al., PGF2 increases uveoscleral outflow,Invest Ophthalmic Vis Sci. (suppl)284 ARVO Abstracts, 1987.
Siebold, et al., Esterfied prostaglandin shows ‘potent’ promise,Prodrug, (5) 3 (1989).
Wartmann, M., et al., The MAP kinase signal transduction pathway is activated by the endogenous cannabinoid anandamide,FEBS Letters, 359, 1995, 133-136.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Prostamides for the treatment of glaucoma and related diseases does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Prostamides for the treatment of glaucoma and related diseases, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Prostamides for the treatment of glaucoma and related diseases will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3760382

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.