Method of controlling site-specific recombination

Multicellular living organisms and unmodified parts thereof and – Method of introducing a polynucleotide molecule into or...

Reexamination Certificate

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C800S260000, C800S287000, C800S288000, C800S306000, C435S069700, C435S462000, C435S468000, C536S023200, C536S023400, C536S023700

Reexamination Certificate

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10353454

ABSTRACT:
The present invention provides methods for the conditional or regulated expression of a site-specific recombinase using split intein-mediated protein splicing. This enhances the temporal and tissue-specificity of trait gene expression and allows for fine tuning of expression specificity.

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