Process for making bicalutamide and intermediates thereof

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitriles

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C558S414000, C560S011000, C562S429000

Reexamination Certificate

active

10682530

ABSTRACT:
Bicalutamide and/or its intermediates are made by the use of p-fluorobenzenesulfinic acid salt as a reagent.

REFERENCES:
patent: 4636505 (1987-01-01), Tucker
patent: 5985868 (1999-11-01), Gray
patent: 6019957 (2000-02-01), Miller et al.
patent: 6583306 (2003-06-01), Ekwuribe
patent: 2005/0033082 (2005-02-01), Bor et al.
patent: 0100172 (1987-08-01), None
patent: WO0058279 (2000-10-01), None
patent: WO0100608 (2001-01-01), None
patent: WO0128990 (2001-04-01), None
patent: WO0134563 (2001-05-01), None
patent: 02/100339 (2002-12-01), None
patent: WO 03/097590 (2003-11-01), None
Gao et al., “Catalytic Asymmetric Epoxidation of Kinetic Resolution: Modified Procedures Including in Situ Derivation”: J. Am. Chem. Soc., 1987, pp. 5765-5780.
Tucker et al., “Nonsteroidal Antiandrogens. Synthesis and Structure-Activity Relationships of 3-Substituted Derivatives of 2-Hydroxypropionanilides”: J. Med. Chem., vol. 31, 1988, pp. 954-959.
Shao et al., “A New Asymmetric Synthesis of α-Methyleysteines via Chiral Aziridines”: J. Org. Chem. vol. 60, 1995, pp. 790-791.
Zeflrov, et al., Journal of Organic Chemistry of the USSR, vol. 22 (2), 1986, pp. 398-399.
Oxley et al. “Amidines. Part II. Preparation of Cyanides, Amides, and Amidines from Carboxylic Acids”: Journal of The Chemical Society, 1946, pp. 763-771.
Johnson et al. “Catalytic Asymmetric Dihydroxylation,” 1993, pp. 227-273.
Johnson et al. “Catalytic Asymmetric Epoxidation of Allylic Alcohols,” 1993, pp. 103-158.
Maryanoff et al., J Med. Chem., vol. 30, 1987, pp. 880-887.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Process for making bicalutamide and intermediates thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for making bicalutamide and intermediates thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for making bicalutamide and intermediates thereof will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3757254

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.