Substituted phenylsulfonamide inhibitors of beta amyloid...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C514S364000, C514S415000, C514S452000, C514S459000, C514S602000, C514S604000, C548S125000, C548S506000, C549S430000, C549S495000, C564S084000, C564S090000, C564S092000, C564S093000

Reexamination Certificate

active

10457641

ABSTRACT:
Compounds of Formula I,wherein R1–R8are defined herein are provided, together with pharmaceutically acceptable salts, hydrates, metabolites, and/or prodrugs thereof. Uses of these compounds for inhibiting beta amyloid production and for the prevention and treatment of Alzheimer's Disease and Down's syndrome are described.

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