Pharmaceutical compositions

Details Pharmaceutical compositions Pharmaceutical compositions

2007-04-17

2007-04-17

Peselev, Elli (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C514S009100, C514S937000, C514S938000, C514S970000, C514S975000, C424S455000

Reexamination Certificate

active

09738104

ABSTRACT:
This invention provides a microemulsion pre-concentrate comprising a difficultly soluble active agent and a carrier medium comprising 1) a hydrophilic phase which comprises dimethylisosorbide and/or a lower alkyl alkanoic ester, 2) a lipophilic phase, and 3) a surfactant. The active agent may be a cyclosporin or a macrolide.In another aspect, this invention provides a pharmaceutical composition for enteral or parenteral administration comprising a macrolide and an acid.

REFERENCES:
patent: 5476843 (1995-12-01), Wohlrab et al.
patent: 5603951 (1997-02-01), Woo
patent: 5639474 (1997-06-01), Woo
patent: 5932243 (1999-08-01), Fricker et al.
patent: 5985321 (1999-11-01), Brox et al.

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