Benzodeazaadenine derivative base and electronic material...

Details Benzodeazaadenine derivative base and electronic material... Benzodeazaadenine derivative base and electronic material...

2007-04-17

2007-04-17

Riley, Jezia (Department: 1637)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S024300, C536S025300, C435S006120

Reexamination Certificate

active

10508138

ABSTRACT:
A nucleic acid base for hole transportation in DNAs which does not cause oxidative decomposition; and an artificial DNA molecule which can realize effective hole transportation in DNAs while maintaining the double spiral structure of the DNAs. Provided are: a nucleic acid which contains a benzodeazaadenine derivative base represented by the general formula (I):(wherein R1, R2, R3, R4, R5, and R6each independently represents hydrogen, amino, mono (lower alkyl) amino, di (lower alkyl) amino, hydroxy, lower alkoxy, halogeno, cyano, mercapto, lower alkylthio, or aryl; and R7and R8each independently represents hydrogen or a group bonded to phosphoric acid);and a polynucleotide comprising the nucleic acid.

REFERENCES:
patent: 0 369 360 (1990-05-01), None
International Search Report Dated Nov. 5, 2002.
Hubschwerlen et al., “Pyrimido [1,6-a]benzimidazoles: A New Class of DNA Gyrase Inhibitors,” J. Med. Chem., vol. 35., No. 8, pp. 1385-1392, American Chemical Society (1992).

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