Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2007-03-27
2007-03-27
Saoud, Christine J. (Department: 1647)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
C435S069700, C435S069800, C530S300000, C530S402000
Reexamination Certificate
active
10063529
ABSTRACT:
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
REFERENCES:
patent: 5536637 (1996-07-01), Jacobs
patent: 5932445 (1999-08-01), Lal et al.
patent: 6025156 (2000-02-01), Gwynn et al.
patent: 6124433 (2000-09-01), Falb et al.
patent: 6156500 (2000-12-01), Falb
patent: 6162604 (2000-12-01), Jacob
patent: 6222029 (2001-04-01), Edwards et al.
patent: 6228582 (2001-05-01), Rodier et al.
patent: 6294343 (2001-09-01), Mack et al.
patent: 6395306 (2002-05-01), Cui et al.
patent: 6414117 (2002-07-01), Levinson
patent: 6465185 (2002-10-01), Goldfine et al.
patent: 6498235 (2002-12-01), Sheppard et al.
patent: 6562343 (2003-05-01), Levinson
patent: 6639063 (2003-10-01), Edwards et al.
patent: 6645499 (2003-11-01), Lal et al.
patent: 6730502 (2004-05-01), Van Hijum et al.
patent: 6737522 (2004-05-01), Sundick et al.
patent: WO 97/38085 (1997-10-01), None
Sen et al. Aneuploidy and cancer (2000), Curr. Opinion in Oncology, vol. 12, pp. 82-88.
Pennica et al. WISP genes are members of the connective tissue growth factor family that are up-regulated in Wnt-1-transformed cells and aberrantly expressed in human colon tumors (1998), PNAS, vol. 95, pp. 14717-14722.
Strausberg et al. (Accession No: Q8WUL1, Jan. 2002).
Haynes et al., Proteone analysis: Biological Assay or data archive? (1998), Electrophoresis, vol. 19, pp. 1862-1871.
Hu et al., Analysis of genomic and Proteomic Data using Advanced literature mining (2003), J. of Proteome Research, vol. 2, pp. 405-412.
Chen et al. Discordant Protein and mRNA Expression in Lung Adenocarcinomas (2002), Molecular and Cellular Proteomics, vol. 1, pp. 304-313.
Heddwen et al. cDNA array identification of genes regulated in rat renal medula in response to vasopressin infusion (2003), Am. J. Physiol. Reanl Physiol., vol. 284: F218-F228.
Berner et al. Clinicopathological associations of CD$$ mRNA and protein expression in primary breast carcinomas (2003), Histopathology, vol. 42, pp. 546-554.
Toler et al. Loss of communication in ovarian cancer (2006), Am. J. of Obs. Gyn., vol. 194, e27-e31.
Sugg et al. Cytoplasmic staining of erb-B-2 but not mRNA levels correlates with differentiation in human thyroid neoplasia (1998), Clinical Endocrinology, vol. 49, pp. 629-637.
Oda et al. Expression of MDR1/p-glycoprotein and multidrug resistance-associated protein in childhood solid tumours (1997), Virchows Arch., vol. 430, pp. 99-105.
Database Search, Protein Sequence Alignments [BLAST 2.2.1 [Jun. 3, 2004]].
Alberts, et al. 1994.Molecular Biology of the Cell, 3rd Edition,pp. 403-404, 453. New York: Garland Publishing.
Alberts, et al. 2002.Molecular Biology of the Cell 4th Edition,pp. 302, 363-364, 379, 435. New York: Garland Publishing.
Grimaldi, et al. 1989. The t(5;14) chromosomal translocation in a case of acute lymphocytic leukemia joins the interleukin-3 gene to the immunoglobulin heavy chain gene.Blood,73(8):2081-2085.
Gygi, et al. Mar. 1999. Correlation between Protein and mRNA Abundance in Yeast.Molecular and Cellular Biology,1720-1730.
Hanna, et al. Aug. 1999. HER-2
eu breast cancer predictive testing.Pathology Associates Medical Laboratories.
Hyman et al. Nov. 2002. Impact of DNA Amplification of Gene Expression Patterns.Cancer Research,62:6240-6245.
Lewin, B. 1994. Oncogenes: Gene Expression and Cancer, Chap. 39. pp. 1196-1201.Genes V.New York: Oxford University Press.
Lewin, B. 1997. Regulation of Transcription, Chap. 29, pp. 847-848.Genes VI.New York: Oxford University Press.
Meeker, et al. 1990. Activation of the interleukin-3 gene by chromosome translocation in acute lymphocytic leukemia with eosinophilia.Blood,76(2):285-289.
Meric, et al. 2002. Translation initiation in cancer: A novel target for therapy.Molecular Cancer Therapeutics,1:971-979.
Ørntoft, et al. 2002. Genome-wide study of gene copy numbers, transcripts, and protein levels in pairs of non-invasive and invasive human transitional cell carcinomas.Molecular&Cellular Proteomics,1:37-45.
Pollack, et al. 2002. Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors.PNAS,99(20):12963-12968.
Singleton, et al. 1992. Clinical and pathologic significance of the c-erbB-2 (HER-2
eu) oncogene.Pathol. Annu,1(27):165-190.
Zhigang, et al. 2004. Prostate stem cell antigen (PSCA) expression in human prostate cancer tissues and its potential role in prostate carcinogenesis and progression of prostate cancer.World Journal of Surgical Oncology,2:13.
2002-2003 Catalog & Technical Reference, New England BioLabs, Inc., p. 122.
Abe, et al. “An increased high-mobility group A2 expression level is associated with malignant phenotype in pancreatic exocrine tissue.”Br J Cancer.Dec. 1, 2003; 89(11):2104-9. (Abstract Only).
Ando, et al. “Selective apoptosis of natural killer-cell tumors by l-asparaginase.”Br. J. Haematol.Sep. 2005;130(6):860-8. (Abstract Only).
Aust, et al. “Human thyroid carcinoma cell lines and normal thyrocytes: expression and regulation of matrix metalloproteinase-1 and tissue matrix metalloproteinase inhibitor-1 messenger-RNA and protein.”ThyroidOct. 1997;7(5):713-24. (Abstract Only).
Barnes, et al. “Expression of embryonic fibronectin isoform ElllA parallels alpha-smooth muscle actin in maturing and diseased kidney.”J Histochem Cytochem.Jun. 1999;47(6):787-98. (Abstract Only).
Bea, et al. “BMl-1 gene amplification and overexpression in hematological malignancies occur mainly in mantle cell lymphomas.”Cancer Res.Mar. 15, 2001;61(6):2409-12. (Abstract Only).
Blaschke, et al. “Rapid quantilation of proinflammatory and chemoattractant cytokine expression in small tissue samples and monocyte-derived dendritic cells: validation of a new real-time RT-PCR technology.”J Immunol Methods.Dec. 1, 2000;246(1-2):79-90. (Abstract Only).
Buckley, et al. “Butyrate-induced reversal of dexamethasone resistance in autonomous rat Nb2 lymphoma cells.” Apoptosis. 1997;2(6):518-28. (Abstract Only).
Caberlotto, et al. “Alterations in neuropeptide Y levels and Y1 binding sites in the Flinders Sensitive Line rats, a genetic animal mode of depression.”Neurosci Lett.Apr. 23, 1999;265(3):191-4. (Abstract Only).
Caberlotto, et al. “Neurokinin 1 receptor and relative abundance of the short and long isoforms in the human brain.”Eur J Neurosci.May 2003;17(9):1736-46. (Abstract Only).
Celis, et al. 2000. Gene expression profiling: monitoring transcription and translation products using DNA microarrays and proteomics.FEBS Letters,480:2-16.
Choi, et al. “Characterization of cyclin D2 expression in human endometrium.” 166:J Soc Gynecol Investig.Jan.-Feb. 2002;9(1):41-6. (Abstract Only).
Couvelard, et al. “Human chorionic gonadotrophin beta expression in malignant Barrett's oesophagus.”Virchows Arch.Sep. 2004;445(3):279-84. Epub Aug. 10, 2004. (Abstract Only).
Crick, F. 1970. Central dogma of molecular biology.Nature,227:561-563.
Dagenais, et al. “Downregulation of ENaC activity and expression by TNF-alpha in alveolar epithelial cells.”Am J Physiol Lung Cell Mol Physiol.Feb. 2004;286(2):L301-11. Epub Sep. 26, 2003. (Abstract Only).
de Boer, et al. “Involvement of the CCND1 gene in hairy cell leukemia.”Ann Oncol.Mar. 1996;7(3):251-6. (Abstract Only).
Debieve, et al. “Inhibin and activin production and subunit expression in human placental cells cultured in vitro.”Mol Hum Reprod.Aug. 2000;6(8):743-9. (Abstract Only).
Dong, et al. “Expression of membrane-type matrix metalloproteinases 4, 5, and 6 in mouse corneas infected withP. aerugi
Goddard Audrey
Godowski Paul J.
Grimaldi J. Christopher
Gurney Austin L.
Wood William I.
Barnes Elizabeth M.
Genentech Inc.
Knobbe Martens Olsen & Bear LLP
Kresnak Mark T.
Saoud Christine J.
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