Sulfonylaminovalerolactams and derivatives thereof as factor...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S363000, C514S384000, C514S415000, C514S444000, C546S193000, C548S262600, C548S136000, C548S469000, C549S059000

Reexamination Certificate

active

10429461

ABSTRACT:
The present application describes sulfonylaminovalerolactams and derivatives thereof of Formula I:or pharmaceutically acceptable salt forms thereof, wherein ring G is a mono- or bicyclic carbocycle or heterocycle. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.

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McMurry, John “Organic Chemistry—Fourth Edition” Brooks/Cole Publishing Company, 1996, p. 694.

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