Treatment of wounds

Details Treatment of wounds Treatment of wounds

2006-12-05

2006-12-05

Swope, Sheridan L. (Department: 1656)

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

C530S333000

Reexamination Certificate

active

07144721

ABSTRACT:
An isolated protein, for use in treatment of wounds, is characterized in that it is secreted by the organismLucilia sericataand it exhibits proteolytic activity against FITC-casein at a pH of 8.0 to 8.5. The protein exhibits proteolytic activity against Tosyl-Gly-Pro-Arg-AMC but not against Suc-Ala-Ala-Phe-AMC, and its proteolytic activity against FITC-casein and Tosyl-Gly-Pro-Arg-AMC is inhibited by the serine proteinase inhibitors PMSF and AMPSF. The protein is also bound by immobilized aminobenzamidine.

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