Benzocycloheptenes, process for their production,...

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C549S078000, C549S415000, C549S427000, C549S502000, C514S277000, C514S438000, C514S451000, C514S461000

Reexamination Certificate

active

07145015

ABSTRACT:
Benzocycloheptenes of formula (I), in which R1, R2and Y have the meanings that indicated herein, exhibit selective estrogenic activity on bones and are suitable for the production of pharmaceutical agents, especially for prophylaxis and therapy of osteoporosis:

REFERENCES:
patent: 6495607 (2002-12-01), Bohlmann et al.
patent: 6878750 (2005-04-01), Bohlmann et al.
patent: 198 06 357 (1998-02-01), None
patent: WO 96 21656 (1996-07-01), None
C.K. Osborne et al., Cancer Chemotherapy and Pharmacology., vol. 34, No. 2, pp. 89-95 (Aug. 1994).
C.S. Murphy et al., Molecular Pharmacology, vol. 39, No. 2, pp. 421-428 (Mar. 1991).
R. McCague et al., Journal of Medicinal Chemistry, vol. 31, No. 7, pp. 1285-1290 (Jul. 1988).
G.M. Anstead et al., Journal of Medicinal Chemistry, vol. 31, No. 7, pp. 1316-1326 (Jul. 1988).
R. McCague et al., Journal of Midicinal Chemistry, vol. 29, No. 10, pp. 2053-2059 (Oct. 1988).
International Search Report mailed Nov. 19, 1999.
Catherino et al., Increased of Tamoxifen Analog, Molecular Endocrinology 1995, vol. 9 #8, pp. 1053-1063.
Database CAPLUS on STN, Acc. No. 1993:94509, Jiang et al., Molecular Endocrinology (1192), 6 (12), p. 2167-74 (Abstract).
Journal of the National Cancer Institute (1993), 85(10), 806-12, (CAPLUS-Abstract AN: 1993:595214).
Molecular Endocrinology (1992); 6(12), 2167-74, (CAPLUS-Abstract AN: 1993:94509).
Molecular Pharmacology (1990), 38(5), 737-43, (CAPLUS-Abstract AN: 1991:55296).
Journal of Medicinal Chemistry (1988), 31(7),1285-90, (CAPLUS-Abstract AN: .1988:422634).
Journal of Medicinal Chemistry (1988), 31(7), 1316-26, (CAPLUS-AbstractAN:1988:422630).
Journal of Medicinal Chemistry (1986), 29(10), 2053-9, (CAPLUS-Abstract AN: 1986:571946).
Emile F. Nuwaysir, et al., “Structure-Activity Relationships for Triphenylethylene Antiestrogens on Hepatic Phase-I and Phase-II Enzyme Expression”, Biochemical Pharmacology, vol. 56, (1998), pp. 321-327.
A. Rosowsky et al., “Methotrexate Analogues. 32. Chain Extension, α-Carboxyl Deletion . . . ”, J. Med. Chem. (1988), 31, pp. 1326-1331.
Office Action issued Mar. 31, 2006 in Korean Application No. 10-2001-7000731 (with English Translation).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Benzocycloheptenes, process for their production,... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Benzocycloheptenes, process for their production,..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Benzocycloheptenes, process for their production,... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3713617

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.