Protein biopolymer markers predictive of type II diabetes

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S007100, C435S007210, C436S063000, C436S086000, C436S089000, C436S173000, C436S178000, C436S501000, C436S518000, C530S300000, C530S350000, C530S387900

Reexamination Certificate

active

07125678

ABSTRACT:
The instant invention involves the use of a combination of preparatory steps in conjunction with mass spectroscopy and time-of-flight detection procedures to maximize the diversity of biopolymers which are verifiable within a particular sample. The cohort of biopolymers verified within such a sample is then viewed with reference to their ability to evidence at least one particular disease state; thereby enabling a diagnostician to gain the ability to characterize either the presence or absence of at least one disease state relative to recognition of the presence and/or the absence of the biopolymer, predict disease risk assessment, and develop therapeutic avenues against the disease.

REFERENCES:
patent: 5062935 (1991-11-01), Schlag et al.
patent: 6020208 (2000-02-01), Hutchens et al.
patent: 0 495 995 (1992-07-01), None
patent: WO86/04144 (1986-07-01), None
patent: WO 90/14148 (1990-11-01), None
patent: WO91/18619 (1991-12-01), None
patent: WO93/15198 (1993-08-01), None
patent: WO 93/24834 (1993-12-01), None
patent: WO 98/07036 (1998-02-01), None
patent: WO 98/53322 (1998-11-01), None
patent: WO 00/49410 (2000-08-01), None
patent: WO01/75454 (2001-10-01), None
Tockman et al. “Consideration in bringing a caner biomarker to clinincal application.” Cancer Research, Suppl. vol. 52, pp. 2711s-2718s, May 1992.
Tascilar et al. Annals of Onocology 10, Suppl. 4:S107-S110, 1999.
Takahashi et al., “Rapid and Sensitive Immunoassay for the Measurement of Serum S100β Using Isoform-specific Monoclonal Antibody”, Clinical Chemistry 45, No. 8, (1999) pp. 1307-1311.
Richter et al., “Composition of the peptide fraction in human blood plasma: database of circulating human peptides”, Journal of Chromatography B; 726 (1999) pp. 25-35.
Aranaga, et al., “Circulating α-actin protein in acute myocardial infarction”, Int'l Journal of Cardiology (1993) vol. 38, No. 1, pp. 49-55.
Database EMBL Online!, Carbone, et al., “A microbial population-species interface: nested cladistic and coalescent inference with multilocus data”, Database accession No. Q9C3LO, EX002237470 abstract.
B. Verges et al, “Macrovascular Disease is Associated with Increased Plasma Apolipoprotein A-IV Levels in NIDDM”, Diabetes, 46(1):125-132 (Jan. 1997).
B. Verges et al, “Apolipoprotein A-IV Levels and Phenotype Distribution in NIDDM”, Diabetes Care, American Diabetes Association, 17(8):810-817 (Aug. 1994).
C. Fievet et al, “Relation of Arteriographically Defined Coronary Artery Disease to Serum Lipoprotein Particles Mapped with Monoclonal Antibodies”, Circulation, 84(1):153-159 (1991).
T. O'Brien et al, “HDL Subparticles and Coronary Artery Disease in NIDDM”, Atherosclerosis, 121(2):285-291 (1996).
P. Jungblut et al, “Proteomics in Human Disease: Cancer, Heart and Infectious Diseases”, Electrophoresis, 20(10):2100-2110 (Jul. 1999).
P. Ebeling et al, “Troglitazone Reduces Hyperglycaemia and Selectively Acute-Phase Serum Proteins in Patients with Type II Diabetes”, Diabetologia, 42(12):1433-1438 (Dec. 1999).
A. Figueredo et al, “Plasma C3d Levels and Ischemic Heart Disease in Type II Diabetes”, Diabetes Care, American Diabetes Association, 16(2):445-449 (Feb. 1993).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Protein biopolymer markers predictive of type II diabetes does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Protein biopolymer markers predictive of type II diabetes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Protein biopolymer markers predictive of type II diabetes will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3710421

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.