Chemistry: molecular biology and microbiology – Vector – per se
Reexamination Certificate
2006-02-14
2006-02-14
Wang, Andrew (Department: 1639)
Chemistry: molecular biology and microbiology
Vector, per se
C435S235100, C435S091500, C435S091500, C536S023100, C536S024100
Reexamination Certificate
active
06998263
ABSTRACT:
The present invention provides a library of viral vectors, wherein each member comprises a first heterologous DNA encoding a first gene product and a second heterologous DNA encoding a second gene product. The first heterologous DNA is common to each member of the library, while the second heterologous DNA varies between members of the library. The present invention additionally provides a method of constructing a library of viral vectors. The method comprises carrying out homologous recombination between a first DNA molecule and a second DNA molecule to form a pool of intermediate viral vector genomes. One or more linear third DNA molecules are ligated into the pool of intermediate viral genomes to produce a library of viral vector genomes. Alternatively, homologous recombination between linear DNA molecules and recipient DNA molecules produces a library of viral vector genomes. The library of viral vector genomes is converted into a library of viral vectors.
REFERENCES:
patent: 5270170 (1993-12-01), Schatz et al.
patent: 5593972 (1997-01-01), Weiner et al.
patent: 5622699 (1997-04-01), Ruoslahti et al.
patent: 5703057 (1997-12-01), Johnston et al.
patent: 5733731 (1998-03-01), Schatz et al.
patent: 5783386 (1998-07-01), Jacobs, Jr. et al.
patent: 5817637 (1998-10-01), Weiner et al.
patent: 5830876 (1998-11-01), Weiner et al.
patent: 5939250 (1999-08-01), Short
patent: 5955275 (1999-09-01), Kamb
patent: 5958672 (1999-09-01), Short
patent: 5981505 (1999-11-01), Weiner et al.
patent: 5989553 (1999-11-01), Johnston et al.
patent: 6001557 (1999-12-01), Wilson et al.
patent: 6156511 (2000-12-01), Schatz et al.
patent: 6440728 (2002-08-01), McVey et al.
patent: 6447768 (2002-09-01), van Zonneveld et al.
patent: WO 94/16737 (1994-08-01), None
patent: WO 95/17511 (1995-06-01), None
patent: WO 96/25506 (1996-08-01), None
patent: WO 96/31613 (1996-10-01), None
patent: WO 97/20918 (1997-06-01), None
patent: WO 98/13485 (1998-04-01), None
patent: WO 98/13487 (1998-04-01), None
patent: WO 98/32860 (1998-07-01), None
patent: WO 98/36097 (1998-08-01), None
patent: WO 98/39483 (1998-09-01), None
patent: WO 98/56937 (1998-12-01), None
patent: WO 99/15686 (1999-04-01), None
patent: WO 99/36516 (1999-07-01), None
patent: WO 99/41368 (1999-08-01), None
patent: WO 99/41369 (1999-08-01), None
patent: WO 99/41383 (1999-08-01), None
patent: WO 99/41402 (1999-08-01), None
patent: WO 99/43843 (1999-09-01), None
patent: WO 99/45151 (1999-09-01), None
patent: WO 99/64582 (1999-12-01), None
patent: WO 00/05406 (2000-02-01), None
patent: WO 01/25463 (2001-04-01), None
Webster's II New Riverside University Dictionary, 1994, Houghton Mifflin Comapny, pp. 690 and 281.
Bett et al.,PNAS USA, 91(1), 8802-8806 (Sep. 1994).
Fu et al.,Hum. Gene Ther., 8(11), 1321-1330 (Jul. 20, 1997).
Hardy et al.,J. Virol., 71(3), 1842-1849 (Mar. 1997).
Murphy et al.,PNAS USA, 84(23), 8277-8281 (Dec. 1987).
Tashiro et al.,Hum. Gene Ther., 10(11), 1845-1852 (Jul. 20, 1999).
Chartier et al.,J. Virol., 70(7), 4805-4810 (1996).
He et al.,PNAS USA, 95(5), 2509-2514 (Mar. 3, 1998).
Imler et al.,Gene Ther., 2(4), 263-268 (Jun. 1, 1995).
Brough Douglas E.
Bruder Joseph T.
Kovesdi Imre
McVey Duncan L.
Wickham Thomas J.
GenVec, Inc.
Leydig , Voit & Mayer, Ltd.
Tran My-Chau T.
Wang Andrew
LandOfFree
Methods of preparing and using a viral vector library does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods of preparing and using a viral vector library, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods of preparing and using a viral vector library will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3705933