Substituted pyrimidine derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C544S297000

Reexamination Certificate

active

07087617

ABSTRACT:
This invention relates to compounds of Formula I,a stereoisomer thereof, a pharmaceutically acceptable salt thereof, a prodrug thereof, or a pharmaceutically acceptable salt of a prodrug thereof. The compounds interact with CRF1receptors, including human CRF1receptors. This invention also relates to methods of using the compounds of the invention to treat a disorder or condition, the treatment of which can be effected or facilitated by antagonizing a CRF receptor, such as CNS disorders or diseases, particularly anxiety-related disorders such as anxiety, and mood disorders such as major depression.

REFERENCES:
patent: 6043260 (2000-03-01), Chen et al.
patent: 1097709 (2000-10-01), None
patent: 9639400 (1996-12-01), None
patent: 0160806 (2001-08-01), None
patent: 0168614 (2001-09-01), None
patent: WO 01/68614 (2001-09-01), None
patent: WO 200168614 (2001-09-01), None

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