Process for preparing free-flowing ethylcellulose microcapsules

Coating processes – Particles – flakes – or granules coated or encapsulated – Solid encapsulation process utilizing an emulsion or...

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2523153, 264 41, 4272133, 4284022, 42840221, 42840224, B05D 700

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active

045420424

ABSTRACT:
A process for preparing free-flowing microcapsules by taking advantage of the phase-separation of ethylcellulose in cyclohexane is disclosed. In this process, a hydrocarbon compound which is soluble in cyclohexane and have a molecular weight of 150 to 3,000 and a solubility parameter (.delta., at 25.degree. C.) of 7 to 10 (cal/cm.sup.3).sup.1/2 is used as the phase-separation-inducing agent.

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D'Onofrio et al., "Encapsulated Microcapsules", International Journal of Pharmaceutics, 2 (1979), 91-99.

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