Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Fungi
Reexamination Certificate
2006-06-27
2006-06-27
Afremova, Vera (Department: 1651)
Chemistry: molecular biology and microbiology
Micro-organism, per se ; compositions thereof; proces of...
Fungi
C435S255100, C435S141000, C435S171000, C435S911000
Reexamination Certificate
active
07067304
ABSTRACT:
The invention relates toMonascus purpureusmutants, which are useful in the preparation of fermentation products having blood pressure lowering activity with a very low amount of citrinin.The invention also provides a process for preparing the fermentation products having blood pressure lowering activity using theMonascus purpureusmutants, and the use of the fermentation products in lowering blood pressure.
REFERENCES:
patent: 4323648 (1982-04-01), Tanzawa et al.
patent: 5472730 (1995-12-01), Saikusa et al.
patent: 6635467 (2003-10-01), Chen et al.
patent: 61197524 (1986-09-01), None
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patent: 2000279163 (2000-10-01), None
patent: 0131048 (2001-05-01), None
Derwent Japan Abstract JP62298598 Dated Dec. 25, 1987 “New Hypotensive Fraction in Culture Broth of Monascus Sp. Mould-Absorbed on Acidic Cation Exchange Region, Washing and Eluting by Pyridine Acetate Buffer” Copyright 1996-1998 Derwent Information Limited.
Derwent Japan Abstract JP2000279163 Dated Oct. 10, 2000 “Manufacture of High Monascus Content Food Having Hypotensive Effect, Involves Using White Rice, Soya Beans or Wheat as Koji-Producing Raw Material and Hydrolyzing to Obtain Koji at Specified Moisture Content” Derwent World Patents Index Copyright 2001.
Japan Abstract of JP61197524 Dated Sep. 1, 1986 T. Shoichi, et al. “Remedy for Hypertension”.
Japan Abstract of JP7274978 Dated Oct. 24, 1995 Endo Akira, et al. “Production of Ang-Khak Colorant”.
Yasuhiro Kohama, et al. Chem. Pharm. Bull. 1987; “Isolation and Identification of Hypotensive Principles in Red-Mold Rice” vol. 35 (6) (1987) pp. 2484-2489.
P.J. Blanc, et al. International Journal of Food Microbiology “Characterization of Monascidin A FromMonascusas Citrinin” vol. 27 (1995) pp. 201-213.
Chen Chien-Cho
Chen Yen-Lin
Hwang Ing-Er
Lin Ming-Chin
Yuan Gwo-Fung
Afremova Vera
Food Industry Research and Development Institute
Ladas and Parry LLP
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