Antihyperlipidemic and antiatherosclerotic compounds and composi

Details Antihyperlipidemic and antiatherosclerotic compounds and composi Antihyperlipidemic and antiatherosclerotic compounds and composi

1988-03-30

1989-09-19

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514542, 514562, 514563, 514585, 514586, 514587, 514595, 514596, 514597, 514598, 514824, 560 10, 560 16, 560 34, 562428, 562439, 564 26, 564 27, 564 28, 564 29, 564 44, 564 49, 564 50, 564 51, 564 52, 564 53, 564 54, 564 56, C07C14940, C07C12717

Patent

active

048682101

ABSTRACT:
Certain N-2,6-dialkyl- or N-2,6-dialkoxyphenyl-N'-arylalkylurea compounds are potent inhibitors of the enzyme acyl CoA:cholesterol acyltransferase (ACAT), and are thus useful agents for the treatment of hypercholesterolemia or atherosclerosis.

REFERENCES:
patent: 2055608 (1936-09-01), Lubs et al.
patent: 3636104 (1972-01-01), Kober et al.
patent: 3674414 (1972-07-01), Kalopissis et al.
patent: 3734961 (1973-05-01), Englehart
patent: 4387105 (1983-06-01), DeVries et al.
patent: 4387106 (1983-06-01), De Vries et al.
patent: 4397868 (1983-08-01), DeVries
patent: 4410697 (1983-10-01), Torok et al.
patent: 4473579 (1984-09-01), Devries et al.
patent: 4623662 (1986-11-01), De Vries

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