Pharmaceutical compositions and methods using certain 4H-pyrano

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514861, 514863, 514830, 514928, A61K 3144

Patent

active

048681920

ABSTRACT:
A pharmaceutical composition comprising, as active ingredient, 9-ethyl-6,9-dihydro-4,6-dioxo-10-propyl-4H-pyrano(3,2-g)quinoline-2,8-dica rbo xylic acid or a pharmaceutically acceptable derivative thereof in admixture with a pharmaceutical acceptable adjuvant or excipient, the composition being suitable for topical administration to a patient's skin but not suitable for administration orally or to the patient's eye.
Also described are methods of treatment of various dermatological disorders comprising topical administration to the skin of a patient suffering from such a disorder of a therapeutically effective quantity of 9-ethyl-6,9-dihydro-4,6-dioxo-10-propyl-4H-pyrano(3,2-g)quinoline-2,8-dica rbo xylic acid or a pharmaceutically acceptable derivative thereof.

REFERENCES:
patent: 4419352 (1983-12-01), Cox et al.
patent: 4474787 (1984-10-01), Cairns et al.
patent: 4760072 (1988-07-01), Brown et al.
Chemical Abstracts, 103:196023 x, (1985).

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