Pyridine-1-oxide derivative, and process for its...

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S318000

Reexamination Certificate

active

07126002

ABSTRACT:
The invention relates to N-[2-hydroxy-3-(1-piperidinyl)-propoxy]-pyridine-1-oxide-3-carboxamidine and its optically active enantiomers. (R)-(−)-N-[2-hydroxy-3-(1-piperidinyl)-propoxy]-pyridine-1-oxide-3-carboxamidine and (S)-(+)-N-[2-hydroxy-3-(1-piperidinyl)-propoxy]-pyridine-1-oxide-3-carboxamidine. Furthermore, the invention relates to the preparation of N-[2-hydroxy-3-(1-piperidinyl)-propoxy]-pyridine-1-oxide-3-carboxyimidoyl chloride, which may be used as an active ingredient of medicaments, and the preparation of the optically active enantiomers of this compound using the compounds of the invention as intermediate substances.

REFERENCES:
patent: 5147879 (1992-09-01), Nagy et al.
patent: 5296606 (1994-03-01), Nagy et al.
patent: 6649628 (2003-11-01), Kurthy et al.
patent: 6653326 (2003-11-01), Vigh et al.
patent: WO 97/13504 (1997-04-01), None
patent: WO 97/16439 (1997-05-01), None
patent: WO 00/50403 (2000-08-01), None

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