Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2006-02-21
2006-02-21
Weber, Jon (Department: 1653)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C530S395000, C530S350000, C530S300000
Reexamination Certificate
active
07001881
ABSTRACT:
The invention features a tribonectin and a method of tribosupplementation carried out by administering tribonectins directly to an injured or arthritic joint.
REFERENCES:
patent: 2487377 (1949-11-01), Roehner et al.
patent: 2734862 (1956-02-01), Morway et al.
patent: 2878184 (1959-03-01), March et al.
patent: 4108849 (1978-08-01), Thomas
patent: 4438100 (1984-03-01), Balslev et al.
patent: 5260417 (1993-11-01), Grant et al.
patent: 5326558 (1994-07-01), Turner et al.
patent: 5510121 (1996-04-01), Rhee et al.
patent: 5510122 (1996-04-01), Sreebny et al.
patent: 5515590 (1996-05-01), Pienkowswki
patent: 5612028 (1997-03-01), Sackier et al.
patent: 5639796 (1997-06-01), Lee
patent: 5702456 (1997-12-01), Pienkowski
patent: 5709020 (1998-01-01), Pienkowski et al.
patent: 6433142 (2002-08-01), Turner et al.
patent: WO 92/13075 (1992-08-01), None
Clark et al. “MSF precursor”, Feb. 2, 1993, Database A—Geneseq—1101, Accession No.: AAR26049, alignment aa1.
Clark et al. “MSF precursor”, Feb. 2, 1993, Database A—Geneseq—1101, Accession No.: AAR26049, alignment aa7.
Clark et al. “MSF precursor”, Feb. 2, 1993, Database A—Geneseq—1101, Accession No.: AAR26049, alignment aa8.
Clark et al. “MSF precursor”, Feb. 2, 1993, Database A—Geneseq—1101, Accession No.:AAR26049, alignment aa2.
Clark et al. “MSF precursor”, Feb. 2, 1993, Database A—Geneseq—1101, Accession No.:AAR26049, alignment aa3.
Clark et al. “MSF precursor”, Feb. 2, 1993, Database A—Geneseq—1101, Accession No.:AAR26049, alignment 200-1140 of SEQ ID No.: 1.
Clark et al. “MSF precursor”, Feb. 2, 1993, Database A—Geneseq—1101, Accession No.: AAR26049, alignment 200-1167 of SEQ ID No.: 1.
Clark et al. “MSF precursor”, Feb. 2, 1993, Database A—Geneseq—1101, Accession No.: AAR26049, alignment 200-1212 of SEQ ID No.: 1.
Clark et al. “MSF precursor”, Feb. 2, 1993, Database A—Geneseq—1101, Accession No.: AAR26049, alignment 200-1263 of SEQ ID No.: 1.
Clark et al. “MSF precursor”, Feb. 2, 1993, Database A—Geneseq—1101, Accession No.: AAR26049, alignment 25-1404 of SEQ ID No.: 1.
Clark et al. “MSF precursor”, Feb. 2, 1993, Database A—Geneseq—1101, Accession No.: AAR26049, alignment aa6.
Clark et al. “MSF Precursor” Feb. 2 1993, Database A—Geneseq—Jun. 19, 2003, Accession No.: AAR26049, Alignment result 1.
Flannery et al. “Bos taurus superficial zone protein mRNA, partial cds” Mar. 5, 1999, Database GenBank, Accession No.: AF056218, Alignment result 2.
Turner et al. Alignment result attached. #1.
Aydelotte et al. (1992) “Heterogeneity of Articular Chondrocytes”,Articular Cartilage and Osteoarthritis, Raven Press Ltd., New York, pp. 237-249.
J.P. Caron (1992) “Understanding the Pathogenesis of Equine Osteoarthritis”,Br. Vet.J.USA, vol. 148, pp. 369-371.
Flannery et al. (1999) “Articular Cartilage Superficial Zone Protein (SZP) is Homologous to Megakaryocyte Stimulating Factor Precursor and is a Multifunctional Proteoglycan with Potential Growth-Promoting, Cytoprotective, anmd Lubricating Properties in Cartilage Metabolism”,Biochemical and Biophysical Communications, vol. 254, pp. 535-541.
Garg et al (1979) “The Structure of the O-Glycosylically-linked Oligosacharide Chains of LPG-I, A Glycoprotein Present in Articular Lubricating Fraction of Bovine Synovial Fluid”Carbohydrate Research, vol. 78, pp. 79-88.
Jay (1992) “Characterization of a Bovine Synovial Fluid Lubricating Factor. l. Chemical, Surface Activity and Lubricating Properties”Connective Tissue Research, vol. 28, pp. 71-88.
Jay et al. (1992) “Characterization of a Bovine Synovial Fluid Lubricating Factor. II. Comparison with Purified Ocular and Salivary Mucin”Connective Tissue Research, vol. 28, pp. 89-98.
Jay et al. (1992) “Characterization of a Bovine Synovial Fluid Lubricating Factor. III. The Interaction with Hyaluronic Acid”Connective Tissue Research, vol. 28, pp. 245-255.
Jay et al. (1990) “Silver Staining of Extensively Glycosylated Proteins on Sodium Dodecyl Sulfate-Polyacrylamide Gels: Enhancement by Carbohydrate-Binding Dyes”,Analytical Biochenistry, vol. 185, pp. 324-330.
Jay et al. (1998) “Comparison of the Boundary-Lubricating Ability of Bovine Synovial Fluid, Lubricin, and Healon”, J Biomed Mater Res, vol. 40, pp. 414-418.
Jay (1990), “Joint Lubrication: A Physicochemical Study of a Purified Lubrication Factor from Bovine Synovial Fluid”, Thesis, Degree of Doctor of Philosophy, Basis Health Sciences (Cellular and Molecular Pathology), State University of New York.
Jay et al. (2000) “Lubricin is a product of megaryocyte stimulating factor gene expression by human synovial fibroblasts”,J. Rheumatology, vol. 27, No. 3, pp. 594-600.
Lorenzo et al. (1998) “A Novel Catilage Protein (CILP)Present in the Mid-zone of Human Articular Cartilage Increases with Age”,J of Biological Chemistry, vol. 273, No. 36, pp. 23463-23468.
Lorenzo et al. (1998) “Cloning and Deduced Amino Acid Sequence of a Novel Cartilage Protein (CILP) Identifies a Proform Including a Nucleotide Pyrophosphohydrolase”,J of Biological Chemistry, vol. 273, No. 36, pp. 23469-23475.
Merberg et al. (1993) “A Comparison of Vitronectin and Megakaryocyte Stimulating Factor”, Elevier Science Publishers, B.V., pp. 45-53.
Merberg et al. (1997) “Megakaryocyte Stimulating Factor”, EMBL Sequence Database XP002152061.
Merberg et al. (1997) “Human Megakaryocyte Stimulating Factor mRNA, complete cds”, EMBL Sequences Database XP002152062.
Schumacher et al. (1999) “Immunodetection and Partial cDNA Sequences of the Proteoglycan, Superficial Zone Protein, Synthesized by Cells Lining Synovial Joints”,J Orthopaedic Research, vol. 17, pp. 110-120.
Schumacher et al. (1994) “A Novel Proteoglycan Synthesized and Secreted by Chondrocytes of the Superficial Zone of Articular Cartilage”,Archives of Biochemistry and Biophysics, vol. 311, pp. 144-152.
Swann et al. (1985) “The Molecular Structure and Lubricating Activity of Lubricin Isolated from Bovine and Human Synovial Fluids”,Biochem J, vol. 225, pp. 195-201.
Swann et al. (1981) “The Molecular Structure of Lubricating Glycoprotein-I, the Boundary Lubricant for Articular Cartilage”,J. Biological Chemistry, vol. 256, No. 11, pp. 5921-5925.
Turner et al. (1991) “Purification, Biochemical Characterization, and Cloning of a Novel Megakaryocyte Stimulating Factor that has Megakaryocyte Colony Stimulating Activity”, Blood, vol. 78 (Suppl. 1), pp. 279.
Clark Paul T.
Clark & Elbing LLP
Mitra Rita
Rhode Island Hospital
Weber Jon
LandOfFree
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