Technology of intracellular delivery of DNA oligonucleotides...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

Reexamination Certificate

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C435S006120, C435S091100, C435S455000, C435S458000, C536S023100

Reexamination Certificate

active

07119078

ABSTRACT:
The present invention relates to methods of intracellular delivery of oligonucleotides. More particularly, the present invention relates to the use of the delivery system to deliver G-quartet oligonucleotides as a cancer therapy or an anti-viral therapy.

REFERENCES:
patent: 6040181 (2000-03-01), Reed
patent: 6288042 (2001-09-01), Rando et al.
patent: WO 97/20924 (1997-06-01), None
M. Nielsen et al. Eur. J. Immunol. vol. 24, pp. 3082-3086 (1994).
J. E. Darnell, Jr. Science, vol. 77, pp. 1630-1635 (1997).
R. Tam et al. J. Immunol. vol. 163, No. 8, pp. 200-208 (1997).
A. Peracchi et al. Rev. Med. Virol. vol. 14, pp. 47-64 (2004).
A. Branch, Trends in Biochem. Sci. vol. 23, pp. 45-50 (1998).
C. A. Stoddart et al. Antimicrobial Agents & Chemotherapy, vol. 42, No. 8, pp. 2113-2115 (1998).
P. J. Bates et al. J. Biol. Chem. vol. 274, No. 37, pp. 26,369-26,377 (1999).
P. J. Bates, et al. Proc. Am. Assoc. Cancer Res. Ann. Mtg. vol. 39, p. 64, Abstract No. 436 (1998).
T. Chirila et al. Biomaterials, vol. 23, pp. 321-342 (2002).
S. Crooke, Antisense Res. and Application, Chapter 1, pp. 1-50, S. Crooke, ed. Publi. Springer-Verlag (1998).
N. Jing, Expert Opinion on Investigational Drugs, vol. 9, No. 8, pp. 1777-1785 (2000).
S. Agrawal et al. Molecular Med. Today, vol. 61, pp. 72-81 (2000).
Jing, Naijie, et al.; Rational Drug Design of DNA Oligonucleotides as HIV Inhibitors; Current Drug Targets—Infectious Disorders, 2001, 1, 79-90.
Jing, Naijie, et al.; Potassium-Induced Loop Conformational Transition of a Potent Anti-HIV Oligonucleotide; Journal of Biomolecular Structure & Dynamics, vol. 15 (3), pp. 573-585, 1997.
Jing, Naijie, et al.; Potassium-Dependent Foldling: A Key to Intracellular Delivery of G-Quartet Oligonucleotides as HIV Inhibitors; Biochemistry, vol. 41 (17), pp. 5397-5403, 2002.
Jing, Naijie, et al.; Structure-Activity of Tetrad-forming Oligonucleotides as a Potent Anti-HIV Therapeutic Drug; The Journal of Biological Chemistry, vol. 273 (52), pp. 34992-34999, Dec. 25, 1998.
Wang, Die, et al.; Stearylamine Liposome as a New Efficient Reagent for DNA Transfection of Eukaryotic Cells; Biochemical and Biophysical Research Communications 226, pp. 450-455, 1996.
Jing, Naijie, et al.; Stability-Activity Relationships of a Family of G-tetrad Forming Oligonucleotides as Potent HIV Inhibitors; The Journal of Biological Chemistry; vol. 275 (5), pp. 3421-3430, Feb. 4, 2000.
Jing, Naijie, et al.; Mechanism of Inhibition of HIV-1 Integrase by G-tetrad-forming Oligonucleotides in Vitro; The Journal of Biological Chemistry, vol. 275 (28), pp. 21460-21467, Jul. 14, 2000.
Jing, Naijie, et al.; Ion Selective Folding of Loop Domains in a Potent Anti-HIV Oligonucleotide; Biochemistry, vol. 36 (41), pp. 12498-12505, 1997.

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