Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form
Reexamination Certificate
2006-11-21
2006-11-21
Kishore, Gollamudi S. (Department: 1615)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Particulate form
C424S499000
Reexamination Certificate
active
07138141
ABSTRACT:
A process for preparing ultrafine powders of biological macromolecules comprises atomizing liquid solutions of the macromolecules, drying the droplets formed in the atomization step, and collecting the particles which result from drying. By properly controlling each of the atomization, drying, and collection steps, ultrafine dry powder compositions having characteristics particularly suitable for pulmonary delivery for therapeutic and other purposes may be prepared.
REFERENCES:
patent: 2598525 (1952-05-01), Fox
patent: 3362405 (1968-01-01), Hazel
patent: 3425600 (1969-02-01), Ablanalp
patent: 3674901 (1972-07-01), Shepherd et al.
patent: 3921637 (1975-11-01), Bennie et al.
patent: 3964483 (1976-06-01), Mathes
patent: 3991304 (1976-11-01), Hillsman
patent: 3991761 (1976-11-01), Cocozza
patent: 3994421 (1976-11-01), Hansen
patent: 4036223 (1977-07-01), Obert
patent: 4069819 (1978-01-01), Valentini et al.
patent: 4098273 (1978-07-01), Glenn
patent: 4153689 (1979-05-01), Hirai et al.
patent: 4211769 (1980-07-01), Okada et al.
patent: 4249526 (1981-02-01), Dean et al.
patent: 4253468 (1981-03-01), Lehmbeck
patent: 4294624 (1981-10-01), Veltman
patent: 4294829 (1981-10-01), Suzuki et al.
patent: 4338931 (1982-07-01), Cavazza
patent: 4446862 (1984-05-01), Baum et al.
patent: 4452239 (1984-06-01), Malem
patent: 4484577 (1984-11-01), Sackner et al.
patent: 4503035 (1985-03-01), Pestka et al.
patent: 4534343 (1985-08-01), Nowacki et al.
patent: 4590206 (1986-05-01), Forrester et al.
patent: 4624251 (1986-11-01), Miller
patent: 4627432 (1986-12-01), Newell et al.
patent: 4649911 (1987-03-01), Knight et al.
patent: 4659696 (1987-04-01), Hirai et al.
patent: 4677975 (1987-07-01), Edgar et al.
patent: 4698328 (1987-10-01), Neer et al.
patent: 4739754 (1988-04-01), Shaner
patent: 4748034 (1988-05-01), Rham
patent: 4790305 (1988-12-01), Zoltan et al.
patent: 4807814 (1989-02-01), Douche et al.
patent: 4811731 (1989-03-01), Newell et al.
patent: 4819629 (1989-04-01), Jonson
patent: 4823784 (1989-04-01), Bordoni et al.
patent: 4833125 (1989-05-01), Neer et al.
patent: 4884565 (1989-12-01), Cocozza
patent: 4889114 (1989-12-01), Kladders
patent: 4907583 (1990-03-01), Wetterlin et al.
patent: 4926852 (1990-05-01), Zoltan et al.
patent: 4942544 (1990-07-01), McIntosh et al.
patent: 4946828 (1990-08-01), Markussen
patent: 4968607 (1990-11-01), Dower et al.
patent: 4984158 (1991-01-01), Hillsman
patent: 4995385 (1991-02-01), Valentini
patent: 5011678 (1991-04-01), Wang et al.
patent: 5017372 (1991-05-01), Hastings
patent: 5027806 (1991-07-01), Zoltan et al.
patent: 5033463 (1991-07-01), Cocozza
patent: 5035237 (1991-07-01), Newell et al.
patent: 5042975 (1991-08-01), Chien et al.
patent: 5048514 (1991-09-01), Ramella
patent: 5049388 (1991-09-01), Knight et al.
patent: 5081228 (1992-01-01), Dower et al.
patent: 5093316 (1992-03-01), Lezdey et al.
patent: 5098893 (1992-03-01), Franks et al.
patent: 5099833 (1992-03-01), Michaels
patent: 5113855 (1992-05-01), Newhouse
patent: 5139016 (1992-08-01), Waser
patent: 5161524 (1992-11-01), Evans
patent: 5180812 (1993-01-01), Dower et al.
patent: 5186164 (1993-02-01), Raghuprasad
patent: 5200399 (1993-04-01), Wettlaufer et al.
patent: 5204108 (1993-04-01), Illum
patent: 5230884 (1993-07-01), Evans et al.
patent: 5254330 (1993-10-01), Canderton et al.
patent: 5260306 (1993-11-01), Boardman et al.
patent: 5290765 (1994-03-01), Wettlaufer et al.
patent: 5295479 (1994-03-01), Lankinen
patent: 5302581 (1994-04-01), Sarin et al.
patent: 5309900 (1994-05-01), Knoch et al.
patent: 5320094 (1994-06-01), Laube et al.
patent: 5320714 (1994-06-01), Brendel
patent: 5331953 (1994-07-01), Andersson et al.
patent: 5354562 (1994-10-01), Platz et al.
patent: 5354934 (1994-10-01), Pitt et al.
patent: 5364838 (1994-11-01), Rubsamen
patent: 5376359 (1994-12-01), Johnson
patent: 5376386 (1994-12-01), Ganderton et al.
patent: 5384133 (1995-01-01), Boyes et al.
patent: 5458135 (1995-10-01), Patton et al.
patent: 5482927 (1996-01-01), Maniar et al.
patent: 5506203 (1996-04-01), Bäckstrōm et al.
patent: 5518998 (1996-05-01), Bäckstrōm et al.
patent: 5580856 (1996-12-01), Prestrelski
patent: 5667806 (1997-09-01), Kantor
patent: 6051256 (2000-04-01), Platz et al.
patent: 6423344 (2002-07-01), Platz et al.
patent: 6582728 (2003-06-01), Platz et al.
patent: 6592904 (2003-07-01), Platz et al.
patent: 0 122 036 (1984-10-01), None
patent: 0 072 046 (1986-01-01), None
patent: 0 237 507 (1987-09-01), None
patent: 0 347 779 (1989-12-01), None
patent: 0 360 340 (1990-03-01), None
patent: 0 383 569 (1990-08-01), None
patent: 0 467 172 (1992-01-01), None
patent: 0 468 914 (1992-01-01), None
patent: 0 490 797 (1992-06-01), None
patent: 0 506 293 (1992-09-01), None
patent: 0 611 567 (1994-08-01), None
patent: 0611567 (1994-08-01), None
patent: 2257351 (1974-01-01), None
patent: 1 527 605 (1978-10-01), None
patent: 7712041 (1979-05-01), None
patent: 0628930 (1978-09-01), None
patent: 1003926 (1983-03-01), None
patent: WO 88/04556 (1988-06-01), None
patent: WO 88/09163 (1988-12-01), None
patent: WO 90/07351 (1990-07-01), None
patent: WO 90/09780 (1990-09-01), None
patent: WO 90/15635 (1990-12-01), None
patent: WO 91/02545 (1991-03-01), None
patent: WO 91/02558 (1991-03-01), None
patent: WO 91/16882 (1991-11-01), None
patent: WO 93/02712 (1993-02-01), None
patent: WO 93/09832 (1993-05-01), None
patent: WO 94/08552 (1994-04-01), None
patent: WO 95/00127 (1995-01-01), None
patent: WO 95/00128 (1995-01-01), None
patent: WO 95/23613 (1995-09-01), None
patent: WO 95/24183 (1995-09-01), None
patent: WO 96/09814 (1996-04-01), None
patent: WO 97/03649 (1997-02-01), None
patent: WO 97/36578 (1997-10-01), None
patent: 94/0155 (1994-01-01), None
Björk, E. et al., “Degradable Starch Microspheres As a Nasal Delivery System for Insulin,”International Journal of Pharmaceutics, 1988, vol. 47, pp. 233-238.
Bohnet, Matthias, “Calculation and Design of Gas/Solid-Injectors,”Powder Tech., 1984, pp. 302-313.
Budrik, G. K. et al., “Ejector Feeders for Pneumatic Transport Systems,”Chemical&Petroleum Engineering, Sep.-Oct. 1978, vol. 14, No. 9-10, pp. 9-10.
Byron, P. R. et al., “Drug Delivery Via the Respiratory Tract,”Journal of Aerosol Medicine, 1994, vol. 7, No. 1, pp. 49-75.
Carpenter, John F. et al., “Modes of Stabilization of a Protein by Organic Solutes During Desiccation,”Cryobiology, 1988, vol. 25, pp. 459-470.
Chien, Y. W. et al., “Intranasal Drug Delivery for Systemic Medications,”CRC Critical Reviews in Therapeutic Drug Carries Systems, 1987, vol. 4, Issue 2, pp. 67-92.
Colthorpe P. et al., “The Pharmacokinetics of Pulmonary-Delivered Insulin: A Comparison of Intratracheal and Aerosol Administration to the Rabbit,”Pharmaceutical Research, 1992, vol. 9, No. 6, pp. 764-768.
Duchateau, G. et al., “Bile Salts and Intranasal Drug Absorption,”International Journal of Pharmaceutics, 1986, vol. 31, pp. 193-199.
Elliott, R. B. et al., “Parenteral Absorption of Insulin From the Lung in Diabetic Children,”Aust. Paediatr. J., 1987, vol. 23, pp. 293-297.
Fox, L. S. et al., “Performance of a Venturi Eductor as a Feeder in a Pneumatic Conveying System,”Powder&Bulk Engineering, Mar. 1988, pp. 33-36.
Friedman. T., “Progress Toward Human Gene Therapy,”Science, Jun. 16, 1989, vol. 244, pp. 1275-1281.
Gánsslen, M. “Uber Inhaltation Von Insulin,”Klin. Wochenschr., Jan. 1925, vol. 4, p. 71, with translation included (3 pages).
Govinda Rao, A. R., “Aerosol Insulin Inhalation Enquiry,”Indian J. Physiol. Pharmacol., 1959, vol. 3, pp. 161-167.
Habener, Joel F., “Parathyroid Hormone: Secretion and Metabolism In Vivo,”Proc. Nat. Acad. Sci., USA, Dec. 1971, vol. 68, No. 12, pp. 2986-2991.
Hastings, Randolph H. et al., “Clearance of Different-Sized Proteins From The Aleveolar Space in Humans and Rabbits,”J. Appl. Physiol., 1992, vol. 73, pp. 1310-1316.
Heinemann, L., et al., “Time-Action Pro
Boardman Terrence
Brewer Thomas
Platz Robert
Kishore Gollamudi S.
Nektar Therapeutics
Patterson & Sheridan LLP
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