Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2006-08-22
2006-08-22
Nolan, Patrick J. (Department: 1644)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C435S069100, C435S325000
Reexamination Certificate
active
07094890
ABSTRACT:
Disclosed are methods and compositions for early diagnosis, monitoring and treatment of cartilage degenerative conditions, including forms of arthritis. In particular, the invention relates to a protein, termed “adlican,” that is differentially transcribed and expressed in human subjects suffering from arthritis, such as osteoarthritis (OA) and rheumatoid arthritis (RA) compared with non-arthritis sufferers, antibodies which recognize this protein, and methods for diagnosing arthritis.
REFERENCES:
Vollhardt. Organic Chemistry WH Freeman and Co. NY Publishers, 1987, p. 1261.
Muzny et al., Genbank accession No. AC004616, Apr. 15, 1998.
Genbank submission Accession No. AC004616, 1998.
Genbank submission Accession No. CAB43220, 1999.
Crowl Robert Mitchell
Luk Daniel C.
Nolan Patrick J.
Novartis AG
Wildman David E.
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