Isolated and purified nucleic acids comprising a gene and a...

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S419000, C435S468000, C536S024100, C536S023600, C800S320000, C800S278000, C800S287000, C800S298000

Reexamination Certificate

active

07060815

ABSTRACT:
An isolated and purified nucleic acid comprising a gene specifically expressed in hop lupulin glands. Hops are dioecious, and only female plants bear cones, the lupulin glands of which contain secondary metabolic products which provide bitterness and flavor to beer. These secondary metabolic products contain some pharmacologically effective compounds. In order to breed a more useful cultivar of hops by manipulating the constituent of such useful secondary metabolic products relying on genetic engineering techniques, this invention provides an isolated and purified nucleic acid comprising a gene specifically expressed in hop lupulin glands. By using this nucleic acid, it is possible to develop a novel method for breeding hops with transformation techniques and molecular selection techniques. Furthermore, the present invention also provides a nucleic acid comprising the regulatory region for specifically expressing genes in lupulin glands. This nucleic acid can be used also for hop breeding.

REFERENCES:
patent: 6562129 (2003-05-01), Hasegawa et al.
GenBank Accession No. AJ430353. Novak et al. (Feb. 2002).
GenBank Accession No. AC166247. Muzny et al. (2005).
Hiroyasu Tobe, et al. “Bone Resorption Inhibitors From Hop Extract”, Biosci, Biotech, Biochem., 61(1). pp. 158-159, 1997.
P.R Sanders, et al., “Comparison of Caulifower Mosaic Virus 35S and Nopaline Synthase Promoters in Transgenic Plants”, Nucleic Acids Research, 15 (4), pp. 1543-1558, 1987.
Suen-Ying Fung, et al., “Conversion of Deoxyhumulone into the Hop Alpha-Acid Humulone”, Phytochemistry, vol. 44, No. 6, pp. 1047-1053, Mar. 1997.
Karin W.M. Zuurbier, et al., “Formation of Aromatic Intermediates in the Biosynthesis of Bitter Acids inHumulus lupulus”, Phytochemistry, vol. 38, No. 1, pp. 77-82, Jan. 1995.
Y. Okada, et al., “A Chalcone Synthase-Like Gene Expressed Specifically in Lupulin Glands of Hop (Humulus lupulus)”, EMBL Sequence Data Library, 2 pages, Jun. 23, 1998.
Norma B. Paniego, et al., “Phlorisovalerophenone Synthase, A Novel Polyketide Synthase from Hop (Humulus lupulusL.) Cones”, European Journal of Biochemistry, vol. 262, pp. 612-616, Jun. 1999.
Sive et al., Nucl. Acids. Res., vol. 16, No. 22, p. 10937 (1988—pub. year).
Likens et al., Crop Sci., vol. 18, pp. 380-386 (pub. 1978).
Speirs et al., Meth. Plant Biochem., vol. 10, pp. 1-32 pub. year—1993.
Sparvoli et al., Plant Mol. Biol., vol. 24, pp. 743-755 pub year—1994.
Kim et al., “A 20 Nucleotide Upstream Element is Essential for the Nopaline Synthase (NOS) Promoter Activity”, 1994, Plant Molecular Biology, vol. 24, pp. 105-117.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Isolated and purified nucleic acids comprising a gene and a... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Isolated and purified nucleic acids comprising a gene and a..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Isolated and purified nucleic acids comprising a gene and a... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3669784

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.