Chromosome DNA coding for human hepatocyte growth factor

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

Reexamination Certificate

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C435S325000, C435S365000, C435S254200, C435S243000, C435S320100, C536S023510

Reexamination Certificate

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07141389

ABSTRACT:
A chromosome DNA which codes for human hepatocyte growth factor, a recombinant expression vector capable of expressing the DNA, a transformant transformed with the expression vector and a method of producing recombinant human hepatocyte growth factor. The DNA and polypeptide of the present invention are expected to serve well for hepatocyte cultivation reagents, liver regeneration promoters, various researches, clinical diagnostic reagents and therapeutic drugs for liver diseases.

REFERENCES:
patent: 5004805 (1991-04-01), Gohda et al.
Seki et al, “Isolation and Expression of CDNA for Different Forms of Hepatocyte Growth Factor . . . ” BBRC, 172 (1) p. 321-327, Oct. 15, 1990.
Winnocker, E. inFrom Genes to Clonesp. 384-389, 1987.
Ayala et al. Modern Genetics. Benjamin/Cummings Publishing Co. 1984, p. 694.
Miyazawa et al. Biochm. biophys. Res. Commun. 163(2): 967-973, Sep. 1989.

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