Aryl aniline β 2 adrenergic receptor agonists

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S653000, C546S157000

Reexamination Certificate

active

07125892

ABSTRACT:
The invention provides novel β2adrenergic receptor agonist compounds of formula (I):wherein R1–R13and w have any of the values described in the specification. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with β2adrenergic receptor activity, and processes and intermediates useful for preparing such compounds.

REFERENCES:
patent: 4894219 (1990-01-01), Baker et al.
patent: 5750701 (1998-05-01), Beeley et al.
patent: 6265581 (2001-07-01), Bell et al.
patent: 6541669 (2003-04-01), Moran et al.
patent: 6576793 (2003-06-01), Moran et al.
patent: 6653323 (2003-11-01), Moran et al.
patent: 6670376 (2003-12-01), Moran et al.
patent: 2002/0022625 (2002-02-01), Walland et al.
patent: 849.794 (1977-04-01), None
patent: 0 147 719 (1985-07-01), None
patent: 52-83379 (1977-07-01), None
patent: WO 95/25104 (1995-09-01), None
patent: WO 00/75114 (2000-12-01), None
patent: WO 01/07026 (2001-02-01), None
patent: WO 01/35947 (2001-05-01), None
patent: WO 01/83462 (2001-11-01), None
patent: WO 02/38544 (2002-05-01), None
Riley et al. “Synergistic activity . . . ” CA 107:211584 (1987).
Tsuzurahara et al. “Antiallergic effects . . . ” CA 91:186691 (1979).
Deyrup et al., “Structure-affinity profile of 8-hydroxycarbostyril-based agonists that dissociate slowly from the β2-adrenoceptor”, Naunyn-Schmiedeberg's Arch Pharmacol, vol. 359: pp. 168-177 (1999).
Isogaya et al., “Binding Pockets of the β1- and β2-Adrenergic Receptors for Subtype-Selective Agonists”, Molecular Pharmacology, vol. 56, pp. 875-885 (1999).
Milecki et al., “Carbostyril Derivatives Having Potent β-Adrenergic Agonist Properties”, vol. 30, pp. 1563-1566, 1987.
Yoshizaki et al., “Sympathomimetic Amines Having a Carbostyril Nucleus”, vol. 19, No. 9, pp. 1138-1142 (1976).

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