Ophthalmic formulation with novel gum composition

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C424S078040, C424S488000

Reexamination Certificate

active

07128928

ABSTRACT:
There is provided a pharmaceutical composition suitable for topical administration to an eye, the composition comprising (a) a pharmacologically effective concentration of an active agent and (b) a combination of at least two ophthalmically compatible polymers comprising a novel gum system. In preferred embodiments of the present invention, the compositions increase the retention time of the active agent in the eye, when compared to compositions with other gums or gum systems.

REFERENCES:
patent: 4136173 (1979-01-01), Pramoda et al.
patent: 4136177 (1979-01-01), Lin et al.
patent: 4136178 (1979-01-01), Lin et al.
patent: 4642305 (1987-02-01), Johansson et al.
patent: 4676976 (1987-06-01), Toba et al.
patent: 4727064 (1988-02-01), Pitha
patent: 4844902 (1989-07-01), Grohe
patent: 4861760 (1989-08-01), Mazuel et al.
patent: 5134127 (1992-07-01), Stella et al.
patent: 5135920 (1992-08-01), Kanamaru et al.
patent: 5212162 (1993-05-01), Missel et al.
patent: 5227372 (1993-07-01), Folkman
patent: 5369095 (1994-11-01), Kee et al.
patent: 5376645 (1994-12-01), Stella et al.
patent: 5403841 (1995-04-01), Lang et al.
patent: 5521222 (1996-05-01), Ali et al.
patent: 5688791 (1997-11-01), Kimura et al.
patent: 5710182 (1998-01-01), Reunamäki et al.
patent: 5776445 (1998-07-01), Cohen et al.
patent: 5795913 (1998-08-01), Lehmussaari et al.
patent: 5837870 (1998-11-01), Pearlman et al.
patent: 5874418 (1999-02-01), Stella et al.
patent: 5888493 (1999-03-01), Sawaya
patent: 5958443 (1999-09-01), Viegas et al.
patent: 5985259 (1999-11-01), Cagle et al.
patent: 6046177 (2000-04-01), Stella et al.
patent: 6133248 (2000-10-01), Stella
patent: 6162449 (2000-12-01), Maier et al.
patent: 6174524 (2001-01-01), Bawa et al.
patent: 6224905 (2001-05-01), Lawrence et al.
patent: 6290729 (2001-09-01), Slepian et al.
patent: 6551584 (2003-04-01), Bandyopadhyay et al.
patent: 2002/0107238 (2002-08-01), Bandyopadhyay et al.
patent: 0 149 197 (1985-07-01), None
patent: 0 312 208 (1989-04-01), None
patent: 0 424 043 (1991-04-01), None
patent: 0 590 655 (1994-04-01), None
patent: 0 642 334 (1995-03-01), None
patent: 0 891 768 (1999-01-01), None
patent: 0 938 903 (1999-09-01), None
patent: 06 345653 (1993-08-01), None
patent: WO 93/17664 (1993-09-01), None
patent: WO 97/10805 (1997-03-01), None
patent: WO 98/47535 (1998-10-01), None
patent: WO 99/24393 (1998-10-01), None
patent: WO 99/06023 (1999-02-01), None
patent: WO 99/24393 (1999-05-01), None
patent: WO 99/43333 (1999-09-01), None
patent: WO 00/42992 (2000-07-01), None
patent: WO 01/01950 (2001-01-01), None
patent: WO 01/19366 (2001-03-01), None
patent: WO 01/96461 (2001-12-01), None
PCT International Search Report, PCT/US03/05361.
Asahi Kasei Kogyo KK, Database WPI, Section Ch., Week 199510, Derwent Publications Ltd., London, GB, Class A96, AN 1995-070221, abstract.
Bekers et al., (1991), Cyclodextrins in the Pharmaceutical Field,Drug Development and Industrial Pharmacy, 17(11), pp. 1503-1549.
Cohen et al., (1997), A Novel in situ-forming ophthalmic drug delivery system from alginates undergoing gelation in the eye,Journal of Controlled Release, 44, pp. 207-208.
Le Bourlais et al., (1998), Ophthalmic Drug Delivery Systems—Recent Advances,Progress in Retinal&Eye Research, vol. 17, No. 1, pp. 33-58.
Loftsson, (1998), Increasing the cyclodextrin complexation of drugs and drug bioavailability through addition of water-soluble polymers,Pharmazie, 53, 11, pp. 733-740.
Szejtli, (1994), Medicinal Applications of Cyclodextrins,Medicinal Research Reviews, vol. 14, No. 3, pp. 353-386.
Zhang & Rees, (1999), A review of recent applications of cyclodextrins for drug delivery,Expert Opinion on Therapeutic Patents, 9, pp. 1697-1717.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Ophthalmic formulation with novel gum composition does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Ophthalmic formulation with novel gum composition, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Ophthalmic formulation with novel gum composition will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3655015

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.