Methods for treating aneurysms

Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Arterial prosthesis – Drug delivery

Reexamination Certificate

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C623S903000, C606S200000

Reexamination Certificate

active

07083643

ABSTRACT:
This invention is directed to methods for treating aneurysms wherein the aneurysmal sac is filled with a non-particulate agent or plurality of such agents and/or with a fluid composition which solidifies in situ. Filling of the aneurysmal sac employs sufficient amount of the non-particulate agent or plurality of such agents and/or the fluid composition to inhibit blood flow into the aneurysm sac. In addition, the methods of this invention also provide for non-endogenous isolation of the parent artery proximal and distal to the aneurysmal sac from systemic blood flow of the treated mammal. The combination of these features provides for treatment of the aneurysmal sac while, at the same time, inhibiting aneurysm formation and/or regrowth in the diseased portions of the arterial wall proximal and distal to the treated aneurysm.

REFERENCES:
patent: 3527224 (1970-09-01), Rabinowitz et al.
patent: 3591676 (1971-07-01), Hawkins et al.
patent: 4938763 (1990-07-01), Dunn et al.
patent: 5213580 (1993-05-01), Slepian et al.
patent: 5421826 (1995-06-01), Crocker et al.
patent: 5458568 (1995-10-01), Racchini et al.
patent: 5542926 (1996-08-01), Crocker
patent: 5569184 (1996-10-01), Crocker et al.
patent: 5575815 (1996-11-01), Slepian et al.
patent: 5580568 (1996-12-01), Greff et al.
patent: 5634946 (1997-06-01), Slepian
patent: 5650447 (1997-07-01), Keefer et al.
patent: 5667767 (1997-09-01), Greff et al.
patent: 5674287 (1997-10-01), Slepian et al.
patent: 5695480 (1997-12-01), Evans et al.
patent: 5702361 (1997-12-01), Evans et al.
patent: 5749915 (1998-05-01), Slepian
patent: 5749922 (1998-05-01), Slepian et al.
patent: 5800538 (1998-09-01), Slepian et al.
patent: 5830178 (1998-11-01), Jones et al.
patent: 5843156 (1998-12-01), Slepian et al.
patent: 5855563 (1999-01-01), Kaplan et al.
patent: 5888546 (1999-03-01), Ji et al.
patent: 5894022 (1999-04-01), Ji et al.
patent: 5914345 (1999-06-01), Slepian et al.
patent: 5921954 (1999-07-01), Mohr, Jr. et al.
patent: 5947977 (1999-09-01), Slepian et al.
patent: 5951599 (1999-09-01), McCrory
patent: RE36370 (1999-11-01), Li
patent: 6007573 (1999-12-01), Wallace et al.
patent: 6007833 (1999-12-01), Chudzik et al.
patent: 6017977 (2000-01-01), Evans et al.
patent: 6096021 (2000-08-01), Helm et al.
patent: 6241719 (2001-06-01), Wallace et al.
patent: 6254628 (2001-07-01), Wallace et al.
patent: 6335384 (2002-01-01), Evans et al.
patent: 6344048 (2002-02-01), Chin et al.
Aletich, et al., “The Remodeling Technique of Balloon-Assisted Guglielmi Detachable Coil Placement in Wide-Necked Anuerysms: Experience at the University of Illinois at Chicago”,J. Neurosurg, 93: 388-396 (2000).
“CANCER, Principles & Practice of Oncology”, 4thEd., vol. 1, “Cancer Treatment”, pp. 545-548 (1993).
Castaneda-Zuniga, et al.,Interventional Radiology, in Vascular Embolotherapy, Part 1, 1:9-32, Williams & Wilkins, Publishers (1992).
Cognard, et al., “Treatment of Distal Aneurysms of the Cerebellar Arteries by Intraaneurysmal Injection of Glue”,Am. J. Neuroradiol., 20: 780-784 (1999).
Fischell, et al., “The Beta-Particle-Emitting Radioisotope Stent (Isostent): Animal Studies and Planned Clinical Trials”,Am. J. Cardiol., 78(suppl 3A): 45-50 (1996).
Fischell, et al., “Low-Dose, β-Particle Emission From “Stent” Wire Results in Complete, Localized Inhibition of Smooth Muscle Cell Proliferation”,Circulation, 90(6): 2956-2963 (1994).
Hill-West, et al., “Inhibition of Thrombosis and Intimal Thickening byin situPhotopolymerization of Thin Hydrogel Barriers”,Proc. Natl. Acad. Sci. USA, 91: 5967-5971 (1994).
Geremia, et al., “Embolization of Experimentally Created Aneurysms with Intravascular Stent Devices”,AJNR, 15: 1223-1231 (1994).
Gomez, et al., “Endovascular Theraphy of Traumatic Injuries of the Extracranial Cerebral Arteries”,Endovascular Therapy and Neurocritical Care15 (4): 789-809 (Oct. 1999).
Hemphili, III, et al., “Endovascular Therapy of Traumatic Injuries of the Intracranial Cerebral Arteries”,Endovascular Therapy and Neurocritical Care15 (4): 811-829 (Oct., 1999).
Jungreis, “The Use of Stents in Endovascular Intervention”,AJNR, 16: 1976-1976 (1995).
Kinugasa, et al., “Direct Thrombosis of Aneurysms with Celluose Acetate Polymer”,J. Neurosurg., 77: 501-507 (1992).
Kinugasa, et al., “Early Treatment of Subarachnoid Hemorrhage After Preventing Rerupture of an Aneurysm”,J. Neurosurg., 83:34-41 (1995).
Kinugasa, et al., “Prophylactic Thrombosis to Prevent New Bleeding and to Delay Aneurysm Surgery”,Neurosurg., 36:661 (1995).
Kinugasa, et al., “Cellulose Acetate Polymer Thrombosis for the Emergency Treatment of Aneurysms: Angiographic Findings, Clinical Experience, and Histopathological Study”,Neurosurg., 34(4): 694-701 (1994).
Laird, et al., “Inhibition of Neointimal Proliferation With Low-Dose Irradiation From a β-Particle Emiting Stent,”Circulation93(3):529-536 (1996).
Malek, et al., “Balloon-assist Technique for Endovascular Coil Embolization of Geometrically Difficult Intracranial Aneurysm”,Neurosurgery, 46(6): 1397-1407 (2000).
Mandai, et al., “Direct Thrombosis of Aneurysms with Cellulose Acetate Polymer: Part I—Results of Thrombosis in Experimental Aneurysms”,J. Neurosurg., 77: 497-500 (1992).
Mericle, et al., “Stenting and Secondary Coiling of Intracranial Internal Carotid Artery Aneurysm: Technical Case Report”,Neurosurgery, 43(5): 1229-1234 (1998).
Moret, et al., “The “Remodeling Technique” in the Treatment of Wide Neck Intracranial Aneurysms”,Interventional Neuroradiology, 3: 21-35 (1997).
Nelson, et al., “Balloon-assisted Coil Embolization of Wide-Necked Aneurysms of the Internal Carotid Artery: Medium-term Angiographic and Clinical Follow-up in 22 Patients”,Am J. Neuroradiol., 22: 19-26 (2001).
Pierot, et al., “Endovascular Treatment of Post-Traumatic Complex Carotid-Cavernous Fistulas, Using the Arterial Approach”,J. Neuroradiol., 19: 79-87 (1992) (document presented in both English and French).
Popowski, et al., “Intra-Arterial90Y Brachytherapy: Preliminary Dosimetric Study Using a Specially Modified Angioplasty Balloon”,Int. J. Radiation Oncology Biol. Phys., 33(3): 713-717 (1995).
Riina, et al. “Future Endovascular Management of Cerebral Aneurysms”,Neurosurgery Clinics of North America, 9(4): 917-921 (1998).
Schopohl, et al., “192IR Endovascular Brachytherapy for Avoidance of Intimal Hyperplasia After Percutaneous Transluminal Angioplasty and Stent Implantation in Peripheral Vessels: 6 Years of Experience”,Int. J. Radiation Oncology Biol. Phys., 36(4): 835-840 (1996).
Slepian, “Polymeric Endoluminal Paving: A Family of Evolving Methods for Extending Endoluminal Therapeutics Beyond Stenting”,Contemporary Interventional Techniques12 (4): 715-737 (1994).
Slepian, et al. “Polymeric Endoluminal Gel Paving: Therapeutic Hydrogel Barriers and Sustained Drug Delivery Depots for Local Arterial Wall Biomanipulation.”Semin. Intervent. Cardiol. 1: 103-116 (1996). (Article not enclosed herewith. Applicant will provide a copy as soon as possible after filing this IDS).
Slepian, et al., “β3-Integrins Rather than β1-Integrins Dominate Integrin-Matrix Interactions involved in Postinjury Smooth Muscle Cell Migration”,American Heart Association, pp. 1818-1827, May 12, 1998.
Slepian, et al., “Pre-Conditioning of Smooth Muscle Cells via Induction of the Heat Shock Response Limits Proliferation Following Mechanical Injury”,Biochemical and Biophysical Research Communications, 225: 600-607 (1996) (Article No. 1217).
Szikora, et al., “Endovascular Treatment of Experimental Aneurysms with Liquid Polymers: The Protective Potential of Stents”,Neurosurgery, 38 (2): 339-347 (1996).
Taki, et al., “Se

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