Somatic transfer of modified genes to predict drug effects

Details Somatic transfer of modified genes to predict drug effects Somatic transfer of modified genes to predict drug effects

2006-05-02

2006-05-02

Ketter, James (Department: 1636)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S235100, C435S320100, C435S325000, C435S455000, C536S023100, C536S023400

Reexamination Certificate

active

07037648

ABSTRACT:
The present invention relates to somatic cell gene transfer methods for mimicking one or more effects of a drug candidate compound. In one aspect, the methods mimic the effect of a drug candidate compound with potential to potentiate or suppress activity of a selected target molecule. In another aspect, the methods provide means of identifying a molecular target for the drug candidate compound. The present methods have a variety of uses including providing identified molecular targets for use in drug screens.

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