Pyrido[2,3-d]pyrimidine-2,7-diamine kinase inhibitors

Details Pyrido[2,3-d]pyrimidine-2,7-diamine kinase inhibitors Pyrido[2,3-d]pyrimidine-2,7-diamine kinase inhibitors

2006-05-30

2006-05-30

Berch, Mark L. (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

C544S279000, C544S244000, C544S117000, C514S264110, C514S234200

Reexamination Certificate

active

07053070

ABSTRACT:
Disclosed are compounds of the formulawherein R2, R5, R6, R7, and R8are as defined herein. These compounds and their pharmaceutical compositions are useful for treating cell proliferative disorders, such as cancer and restenosis. These compounds are potent inhibitors of cdks and growth factor-mediated kinases.

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