Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2006-05-23
2006-05-23
Kunz, Gary (Department: 1647)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
C435S069100, C435S071100, C435S320100, C435S471000, C514S013800, C530S351000
Reexamination Certificate
active
07049401
ABSTRACT:
DNAs encoding the human histamine H3 receptor have been cloned and characterized. The recombinant protein is capable of forming biologically active histamine H3 receptor protein. The cDNA's have been expressed in recombinant host cells which produce active recombinant protein. The recombinant protein is also purified from the recombinant host cells. In addition, the recombinant host cells are utilized to establish a method for identifying modulators of the receptor activity, and receptor modulators are identified.
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Erlander Mark
Huvar Arne
Lovenberg Timothy W.
Pyati Jayashree
Hamud Fozia
Kunz Gary
Ortho -McNeil Pharmaceutical, Inc.
Woodcock & Washburn LLP
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