Aldehyde dehydrogenase gene

Details Aldehyde dehydrogenase gene Aldehyde dehydrogenase gene

2006-11-14

2006-11-14

Saidha, Tekchand (Department: 1652)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing oxygen-containing organic compound

C435S136000, C435S140000, C435S252300, C435S254200, C435S410000, C435S320100, C536S023200

Reexamination Certificate

active

07135315

ABSTRACT:
The present invention relates to a novel DNA which encodes aldehyde dehydrogenase (SNDH), an expression vector containing the DNA and recombinant organisms containing said DNA. Furthermore, the present invention concerns a process for producing recombinant aldehyde dehydrogenase protein and a process for producing L-ascorbic acid (vitamin C) and/or 2-keto-L-gulonic acid (2-KGA) from L-sorbosone by using the recombinant aldehyde dehydrogenase protein or recombinant organisms containing the expression vector. Also provided is a process for the production of 2KGA with a microorganism in which the gene encoding said aldehyde dehydrogenase is disrupted.

REFERENCES:
patent: 5437989 (1995-08-01), Asakura et al.
patent: 0 790 301 (1997-08-01), None
patent: 2002-125689 (2002-05-01), None
patent: WO 89/06688 (1989-07-01), None
patent: WO 02/34919 (2002-05-01), None
Miyazaki T. et al. Pyrroloquinoline Ouinone-Dependent Dehydrogenases from Ketogluconicum vulgare Catalyze the Direct Conversion of L-Sorbosone to L-Ascorbic Acid, Applied and Environmental Microbiology, 2006, 72, 1487-1495.
Saito, Y. et al., “Direct Fermentation of 2-Keto-L-Gulonic Acid in Recombinant Gluconobacter oxydans,”Biotechnology and BioEngineering., vol. 58, No. 2&3, pp. 309-315 (1998).
Saito, Y. et al., “Cloning of Genes Coding forL-Sorbose andL-Sorbosone Dehydrogenases from Gluconobacter oxydans and Microbial Production of 2-Keto-L-Gulonate, a Precursor ofL-Ascorbic Acid, in a Recombinant G. oxydans Strain,”Applied and Environmental Microbiology, vol. 63, pp. 454-460 (1997).
Hoshino, T. et al., “Isolation and Characterization of NAD(P)-DependentL-Sorbosone Dehydrogenase from Gluconobacter melanogenus UV10,”Agric. Biol. Chem., vol. 55, No. 3, pp. 665-670 (1991).
Asakura and Hoshino, “Isolation and Characterization of A New Quinoprotein Dehydrogenase,L-Sorbose/L-Sorbosone Dehydrgenase,”Biosci. Biotechnol. Biochem, vol. 63, No. 1, pp. 46-53 (1999).
Hancock and Viola, “Biotechnological approaches forL-ascorbic acid production,”Trends in Biotechnology, vol. 20, No. 7 (2002).
Derwent Database English language abstract of JP 2002-125689 (document B4 above).

Affiliated with

Also associated with

Rating

Aldehyde dehydrogenase gene does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Aldehyde dehydrogenase gene, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Aldehyde dehydrogenase gene will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3642384