Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2006-10-31
2006-10-31
O'Hara, Eileen B. (Department: 1647)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C514S396000, C424S130100, C435S007100
Reexamination Certificate
active
07129207
ABSTRACT:
The present invention relates to a novel human K+ion channel, to nucleic acid molecules encoding the same and to vectors comprising said nucleic acid molecules. The invention additionally relates to antibodies specifically directed to the novel K+ion channel and to pharmaceutical compositions and diagnostic kits containing at least one of the above-mentioned components. Furthermore, the present invention relates to methods of treating a disease caused by malfunction of the polypeptide of the present invention or by the (over)expression of the nucleic acid molecule of the invention comprising administering an inhibitor of said (over)expression or of ion channel function or an inhibitor abolishing said malfunction to a patient in need thereof. Methods of devising drugs for treating or preventing the above-mentioned disease, methods of inhibiting cell proliferation and methods of prognosing cancer are additional embodiments comprised by the present invention. The invention also envisages specific antisense or gene therapies on the basis of the nucleic acid molecule of the invention for inhibiting undesired cellular proliferation, for example, in connection with cancer or in neurodegenerative diseases.
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Beckh Synnove
Bruggemann Andrea
Del Camino Fernandez-Miranda Donato
Pardo-Fernandez Luis A
Sanchez Perez Araceli
Fish & Neave IP Group Ropes & Gray LLP
Haley Jr. James F.
Max-Planck-Gesellschaft zur Forderung Wissenschaften e.V.
O'Hara Eileen B.
Wegert Sandra
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