Enhanced immune response to an antigen by a composition of a rec

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant virus encoding one or more heterologous proteins...

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4242321, 4242041, 4242151, 4242171, 424 931, 424 9321, 4242781, 4242771, 4242811, 4352351, 4353201, 530350, 5303871, 536 2372, A61K 3900, C12N 1500

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06045802&

ABSTRACT:
The present invention is a composition of recombinant virus which has incorporated into its genome or portion thereof a gene encoding an antigen to a disease causing agent and a recombinant virus which has incorporated into its genome or portion thereof a gene encoding an immunostimulatory molecule(s) for the purpose of stimulating an immune response against the disease causing agent. Methods of treatment of diseases such as cancer and diseases caused by pathogenic microorganisms is provide using the composition.

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