Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Reexamination Certificate
2006-04-25
2006-04-25
Qian, Celine (Department: 1636)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
C435S320100, C435S325000, C536S023100
Reexamination Certificate
active
07033792
ABSTRACT:
The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the secreted peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the secreted peptides, and methods of identifying modulators of the secreted peptides.
REFERENCES:
patent: 6461850 (2002-10-01), Beasley et al.
patent: PCT/US01/26345 (2002-07-01), None
Results of BLAST search of SEQ ID NO:2 against Derwent (FastAlert and GeneSeqP) and NCBI (pataa) protein patent databases on Oct. 9, 2003.
Elaroussi et al. “A New Member to the Astasin Family of Metalloendopeptidases: a Novel 1,25-dihydroxyvitamin D-3 Stimulated mRNA From Chorioallantoic Membrane of Quail.” Biocim Biophys Acta. Jan. 1994, vol. 1217, No. 1, pp. 1-8.
International Search report dated Jun. 23, 2003.
Elaroussi, Mahmoud A. et al. “A new member to the astasin family of metalloendopeptidases: A novel 1,25-dihydroxyvitamin D-3-stimulated mRNA from chorioallantoic membrane of quail.” Biochimica et Biophysica Acta, vol. 1217 (1994) pp. 1-8.
-& Database EMBL'Online! Nov. 1, 1995, Elaroussi M.A. et al. “Astacin like metalloendopeptidase (EC 3.4.24.-)” Database accession No. P42662.
-& Database EMBL 'Online! Aug. 23, 1994, Elaroussi, M.A. et al. “Coturnix japonica astacin like metalloendopeptisade mRNA, complete cds.” Database accession No. U12642; S68488.
Database EMBL 'Online!, Oct. 25, 1999, Sulston, J.E. et al. “Homo sapiensBAC clone RP11-574017 from 2, complete sequence.” Database accession No. AC012307.
Database EMBL 'Online!, Jun. 18, 2001, Dias Neto, E. et al. “IL3-UT0117-070301-494-H12 UT0117Homo sapienscDNA, mRNA sequence.” Database accession No. B1061462.
Yasumasu, Shigeki et al., “Isolation of cDNAs for LCE and HCE, Two Constituent Proteases of the Hatching Enzyme ofOryzias latipes,and Concurrent Expression of Their mRNAs during Development.” Developmental Biology vol. 153 (1992), pp. 250-258, Tokyo, Japan.
-& Database EMBL 'Online!, Jul. 1, 1993, Yasumasu, S. et al. “High choriolytic enzyme 2 precursor (EC 3.4.24.67) (Hatching enzyme zinc-protease HCE 2 subunit) (Choriolysin H 2).” Database accession No. P31581.
-& Database EMBL 'Online!, Aug. 21, 1992, Yasumasu, S. et al. “Oryzias latipeshatching enzyme constituent protease (hce) mRNA, complete cds.” Database accession No. M96171.
Database EMBL'Online!, Nov. 1, 1997 Eldering, J.A. et al. “Meprin A beta-subunit precursor (EC 3.4.24.18) (Endopeptidase-2) (N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase beta subunit) (PABA peptide hydrolase) (PPH beta).” Database accession No. Q16820.
Beasley Ellen M.
Yan Chunhua
Zhong Jennifer Min
Applera Corporation
Genomics Celera
Karjala Justin D.
Qian Celine
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