Controlled/modified release oral methylphenidate formulations

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form

Reexamination Certificate

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Details

C424S451000, C424S452000, C424S457000, C424S458000, C424S464000, C424S465000, C424S468000, C424S469000, C424S489000

Reexamination Certificate

active

07083808

ABSTRACT:
The invention is directed to oral modified/controlled release methylphenidate formulations which provide a rapid initial onset of effect and a prolonged duration of effect. Preferably, the peak concentration is lower than that provided by the reference standard for immediate release methylphenidate formulations, and the duration of effect falls rapidly at the end of the dosing interval so as not to affect the appetite of the patient at dinner nor the patient's sleep thereafter.

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