Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-06-27
2006-06-27
Saeed, Kamal A. (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S235500, C514S307000, C514S314000, C514S318000, C514S323000, C514S331000, C546S144000, C546S146000, C546S153000, C546S168000, C546S192000, C546S193000, C546S196000, C546S207000, C546S208000, C546S224000, C544S129000
Reexamination Certificate
active
07067533
ABSTRACT:
The present invention relates to an aminophenoxyacetamide derivative of the formula (I):wherein R1to R4are, independent from each other, a hydrogen atom or an optionally substituted alkyl group; E1is —NR4—; and E2is an oxygen atom or —NR10—; Q is the group —X—Y-Q′, wherein X and Y are connecting bonds or X is an alkylene or alkenylene group and Y is selected from a group comprising C═O, NHC(═), and C(═O)NH, and Q′ is a hydrogen atom or a phenyl or pyridyl group which may be substituted; and pharmaceutically acceptable salts thereof. The present invention further relates to compositions comprising compounds of the formula (I) and methods of using said compounds for treating cerebral functional disorders and cerebral organic disorders.
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McMahon et al., “Calbindin-D28kbuffers intracellular calcium and promotes resistance to degeneration in PC12 cells”,Molecular Brain Research, 1998, 54:56-63.
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Annoura Hirokazu
Murayama Norihito
Takemoto Naohiro
Coppins Janet L.
Daiichi Asubio Pharma Co., Ltd.
Saeed Kamal A.
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