Mammalian alpha-kinase proteins, nucleic acids and...

Details Mammalian alpha-kinase proteins, nucleic acids and... Mammalian alpha-kinase proteins, nucleic acids and...

2006-08-08

2006-08-08

Hutson, Richard (Department: 1652)

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

C435S194000, C435S183000, C435S320100, C435S252300, C536S023100, C536S023200, C536S023700, C530S350000

Reexamination Certificate

active

07087427

ABSTRACT:
The present invention provides novel mammalian alpha-kinase proteins: melanoma alpha-kinase (MK), heart alpha-kinase (HK), kidney alpha-kinase (KK), skeletal muscle alpha-kinase (SK), and lymphocyte alpha-kinase (LK). In particular, a novel kinase type is herein provided, characterized by the presence of an alpha-kinase catalytic domain and an ion channel domain. Isolated nucleic acids of the alpha-kinases MK, HK, KK, SK and LK are provided. Methods for making the novel alpha-kinases, cells that express the alpha-kinases and methods for treating an animal in need of either increased or decreased activity of the alpha-kinases are provided.

REFERENCES:
patent: WO 00/40614 (2000-07-01), None

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