Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2006-08-22
2006-08-22
Forman, BJ (Department: 1634)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C436S504000, C536S023100, C536S024310
Reexamination Certificate
active
07094535
ABSTRACT:
Methods are described for the isolation of nucleic acid ligands to integrins using the SELEX process. SELEX is an acronym for Systematic Evolution of Ligands by EXponential enrichment. The nucleic acid ligands of the present invention are useful as therapeutic and diagnostic agents.
REFERENCES:
patent: 5475096 (1995-12-01), Gold et al.
patent: 5683867 (1997-11-01), Biesecker et al.
patent: 5723323 (1998-03-01), Kauffman et al.
patent: 2 183 661 (1987-06-01), None
patent: WO89/06694 (1989-07-01), None
patent: WO 91/19813 (1991-12-01), None
patent: WO92/14843 (1992-09-01), None
Joyce (1989) Gene 82:83.
Joyce & Inoue (1989) Nucleic Acids Research 17:711.
Ellington & Szostak (May 1990) Abstracts of papers presented at the 1990 meeting on RNA Processing, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, p. 84.
Kinzler & Vogelstein (1989) Nucleic Acids Research 17:3645.
Kramer et al. (1974) J. Mol. Biol. 89:719.
Levisohn & Spiegelman (1969) Proc. Natl. Acad. Sci. USA 63:805.
Levisohn & Spiegelman (1968) Proc. Natl. Acad. Sci. USA 60:866.
Oliphant et al. (1989) Mol. Cell. Biol. 9:2944.
Oliphant & Struhl (1988) Nucleic Acids Research 16:7673.
Oliphant & Struhl (1987) Methods in Enzymology 155:568.
Oliphant et al. (1986) Gene 44:177.
Robertson & Joyce (1990) Nature 344:467.
Thiesen & Bach (1990) Nucleic Acids Research 18:3203.
Szostak, “Structure and Activity of Ribozymes,” inRedesigning the Molecules of Life, (S.A. Benner ed.) Springer-Verlag Berline Heidelberg, pp. 87-113 (1988).
Blind et al. (1999)Proc. Natl. Acad. Sci. USA96:3606.
Gold et al. (1995)Annual Rev. Biochem. 64:763.
Gold Larry
Janjic Nebojsa
Ruckman Judy
Stephens Andrew
Forman BJ
Gilead Sciences, Inc.
Swanson & Bratschun LLC
Zitomer Stephanie
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