Pyridomorphinans, thienomorphinans and use thereof

Details Pyridomorphinans, thienomorphinans and use thereof Pyridomorphinans, thienomorphinans and use thereof

2006-09-12

2006-09-12

Morris, Patricia L. (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

active

07105675

ABSTRACT:
Compounds represented by the formulae:wherein each of Y, X and R individually is selected from the group consisting of hydrogen, hydroxy, halo, CF3, NO2, CN, NH2, COR1and CO2R2wherein R1is selected from the group consisting of alkyl, aryl, alkaryl, and NH2, and R2is selected from the group consisting of alkyl, aryl and aralkyl, and provided that at least one of Y, X and R is other than H; and pharmaceutically acceptable salts thereof are provided. Compounds of the above formula are useful as analgesics for treating pain, as immunomodulators and for treating drug abuse.

REFERENCES:
patent: 4816586 (1989-03-01), Portoghese
patent: 5223507 (1993-06-01), Dappen et al.
patent: WO-96/02545 (1996-02-01), None

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