C-pyrazole A 2A receptor agonists

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

Reexamination Certificate

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Details

C514S045000, C514S047000, C536S027300, C536S027600, C536S027610, C536S027700

Reexamination Certificate

active

07109180

ABSTRACT:
2-adenosine C-pyrazole compounds having formula (a) and methods for using the compounds as A2A receptor agonists to stimulate mammalian coronary vasodilatation for therapeutic purposes and for purposes of imaging the heart

REFERENCES:
patent: 4956345 (1990-09-01), Miyasaka et al.
patent: 5189027 (1993-02-01), Miyashita et al.
patent: 5270304 (1993-12-01), Kogi et al.
patent: 5459254 (1995-10-01), Yamaguchi et al.
patent: 5593975 (1997-01-01), Cristalli
patent: 5705491 (1998-01-01), Yamada
patent: 5770716 (1998-06-01), Khan et al.
patent: 5939543 (1999-08-01), Morozumi et al.
patent: 6026317 (2000-02-01), Verani
patent: 6214807 (2001-04-01), Zablocki et al.
patent: 965411 (1975-04-01), None
patent: 0 354 638 (1990-02-01), None
patent: S48-26038 (1973-08-01), None
patent: 5-9197 (1993-01-01), None
patent: WO 98/52611 (1998-11-01), None
patent: WO 98/57651 (1998-12-01), None
Marumoto, et al., “Synthesis and Coronary Vadodilating Activity of 2-Substituted Adenosines”,Chem . . . Pharm. Bull. 23(4): 759-774 (1975).
Marumoto, et al., “Synthesis and Enzymatic Activity of Adenosine 3'5'-Cyclic Phosphate Analogs”, Chem. Pharm. Bull. 27(4) 990-1003 (1979).
Persson, et al., “Synthesis and Antiviral Effects of 2-Heteroaryl Substituted Adenosine and 8-Heteroaryl Substituted Guanosine Derivatives”,Bioorganic&Medicinal Chemistry, 3:1377-1382 (1995).
Mager, et al., “Molecular simulation applied to 2-(N'alkylidenehydrazino)- and 2-(N'aralkylidenehydrazino) adenosine A2Agnonists”,Eur J. Med. Chem, 30:15-25 (1995).
Cristalli et al., “2-Alkynl Derivatives of Adenosine 5'-N'ethyluronamide: Selective A2Adenosine Receptor Agonists with Potent Inhibitory Activity on Platelet Aggregation”,J. Med. Chem, 37:1720-1726 (1994).
Matsuda, et al., “Nucleosides and Nucleotides. 103. 2-Alkynyladenoines: A Novel Class of Selective Adenosine A2Receptor Agonists with Potent Antihypertensive Effects”,J. Med. Chem. 35:241-252 (1992).

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